Evidence map›Paper›PMID 33652703›Full record

ArticleMetabolites2021

Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models.

Jinny Sun, Robert A Bok, Justin DeLos Santos, Deepti Upadhyay, Romelyn DeLos Santos, Shubhangi Agarwal, Mark Van Criekinge, Daniel B Vigneron, Rahul Aggarwal, Donna M Peehl and 2 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Metabolic changes during prostate cancer development and progression.Journal of cancer research and clinical oncology · 2023
    Review
  11. Review
  12. Review
  13. Targeting Glutamine Metabolism in Prostate Cancer.Frontiers in bioscience (Elite edition) · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jinny SunGraduate Program in Bioengineering, University of California, Berkeley and University of California, San Francisco, CA 94143, USA.
Robert A BokDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
Justin DeLos SantosDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
Deepti UpadhyayDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
Romelyn DeLos SantosDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
Shubhangi AgarwalDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
Mark Van CriekingeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
Daniel B VigneronDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
Rahul AggarwalHematology/Oncology, University of California, San Francisco, CA 94143, USA.
Donna M PeehlDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.
John KurhanewiczDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.ORCID 0000-0002-3544-5339
Renuka SriramDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA.ORCID 0000-0003-3505-2479
University of California, San Francisco · US

Funding

TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9M
YTTRIUM HYPERPOLARIZATIONP41RR002584 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI BAXTER, JEANNIE · 1985 to 2011
$14.3M
Targeting Neuroendocrine Prostate Cancer Using Multi-Probe Hyperpolarized 13C MRI for Improved Treatment and Therapeutic MonitoringR01CA215694 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AGGARWAL, RAHUL, KURHANEWICZ, JOHN · 2017 to 2021
$3.3M
NCI NIH HHS R01 CA215694NCRR NIH HHS P41 RR002584NIH HHS P41EB013598NIH HHS R01CA215694U.S. Department of Defense PC160630
6 · The paper itself

Abstract

Currently, no clinical methods reliably predict the development of castration-resistant prostate cancer (CRPC) that occurs almost universally in men undergoing androgen deprivation therapy. Hyperpolarized (HP)

Indexed as

androgen-dependentcastration-resistantglycolysishyperpolarized [1-13C]pyruvatelactatemagnetic resonancemetabolismprostate cancerTRAMP

Identifiers

PMID33652703
PMCPMC7996870
OpenAlexW3135405660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.