Evidence map›Paper›PMID 33652680›Full record

ArticleBrain sciences2021

Action Observation Therapy for Upper Limb Recovery in Patients with Stroke: A Randomized Controlled Pilot Study.

Mauro Mancuso, Serena Di Tondo, Enza Costantini, Alessio Damora, Patrizio Sale, Laura Abbruzzese

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06794749 nacompletednot on this mapstarted 2025, after this paper: background citation

Investigation of the Effect of Action Observation Therapy Applied With Telerehabilitation Method on Upper Extremity Functions, Daily Living Activities and Quality of Life in Chronic Stroke Patients

TypeinterventionalSponsorKarabuk UniversityRan2025 to 2025Enrolled26ConditionsStrokeArmsAction Observation Therapy, Control
NCT07631169 narecruitingnot on this mapstarted 2026, after this paper: background citation

Investigation of the Effects of Action Observation Therapy Including Unimanual and Bimanual Activities on Upper Extremity Functions, Activities of Daily Living, and Quality of Life in Chronic Stroke

TypeinterventionalSponsorKarabuk UniversityRan2026 to 2027Enrolled45ConditionsChronic StrokeArmsAction Observation Therapy(unimanuel activities), Action Observation Therapy(bimanuel activities), conventional physiotherapy
NCT07631182 narecruitingnot on this mapstarted 2026, after this paper: background citation

Investigation of the Effect of Action Observation Therapy Via Telerehabilitation Method on Upper Extremity Functions, Daily Living Activities and Quality of Life in Chronic Stroke Patients

TypeinterventionalSponsorKarabuk UniversityRan2026 to 2026Enrolled30ConditionsChronic StrokeArmsConventional physiotherapy
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Action observation for upper limb rehabilitation after stroke.The Cochrane database of systematic reviews · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mauro MancusoPhysical and Rehabilitative Medicine Unit, NHS-USL Tuscany South-Est, Via Senese 169, 58100 Grosseto (GR), Italy.ORCID 0000-0002-8451-9277
Serena Di TondoTuscany Rehabilitation Clinic, Montevarchi, Piazza del Volontariato 2, Montevarchi, 52025 Arezzo (AR), Italy.
Enza CostantiniPhysical and Rehabilitative Medicine Unit, NHS-USL Tuscany South-Est, Via Senese 169, 58100 Grosseto (GR), Italy.
Alessio DamoraTuscany Rehabilitation Clinic, Montevarchi, Piazza del Volontariato 2, Montevarchi, 52025 Arezzo (AR), Italy.
Patrizio SaleSant'Isidoro Hospital, FERB Onlus, Via Ospedale 34, 24069 Trescore Balneario (BG), Italy.ORCID 0000-0002-4850-3673
Laura AbbruzzeseTuscany Rehabilitation Clinic, Montevarchi, Piazza del Volontariato 2, Montevarchi, 52025 Arezzo (AR), Italy.
Agenzia Sanitaria Regionale Abruzzo · ITFondazione Europea Ricerca Biomedica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the complexity of the interventions for upper limb recovery, at the moment there is a lack of evidence regarding innovative and effective rehabilitative interventions. Action Observation Training (AOT) constitutes a promising rehabilitative method to improve upper limb motor recovery in stroke patients. The aim of the present study was to evaluate the potential efficacy of AOT, both in upper limb recovery and in functional outcomes when compared to patients treated with task oriented training (TOT). Both treatments were added to traditional rehabilitative treatment. Thirty-two acute stroke patients at 15.6 days (±8.3) from onset, with moderate to severe upper limb impairment at baseline following their first-ever stroke, were enrolled and randomized into two groups: 16 in the experimental group (EG) and 16 in the control group (CG). The EG underwent 30 min sessions of AOT, and the CG underwent 30 min sessions of TOT. All participants received 20 sessions of treatment for four consecutive weeks (five days/week). The Fugl-Meyer Assessment for Upper Extremity (FMA-UE), Box and Block Test (BBT), Functional Independence Measure (FIM) and Modified Ashworth Scale (MAS) were administered at baseline (T

Indexed as

action observationmirror neuronsrehabilitationstrokeupper limb

Identifiers

PMID33652680
PMCPMC7996947
OpenAlexW3133773461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.