Evidence map›Paper›PMID 33652672›Full record

ArticleInternational journal of molecular sciences2021

Synthesis of Novel Pyrido[1,2-

Marek Król, Grzegorz Ślifirski, Jerzy Kleps, Szymon Ulenberg, Mariusz Belka, Tomasz Bączek, Agata Siwek, Katarzyna Stachowicz, Bernadeta Szewczyk, Gabriel Nowak and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Diverse Biological Activity of Pyrimidine Derivatives: A Review.Current drug discovery technologies · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Marek KrólDepartment of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097 Warsaw, Poland.
Grzegorz ŚlifirskiDepartment of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097 Warsaw, Poland.ORCID 0000-0003-0903-0567
Jerzy KlepsDepartment of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097 Warsaw, Poland.
Szymon UlenbergDepartment of Pharmaceutical Chemistry, Medical University of Gdańsk, 107, J. Hallera Street, 80-416 Gdańsk, Poland.ORCID 0000-0001-6599-5502
Mariusz BelkaDepartment of Pharmaceutical Chemistry, Medical University of Gdańsk, 107, J. Hallera Street, 80-416 Gdańsk, Poland.
Tomasz BączekDepartment of Pharmaceutical Chemistry, Medical University of Gdańsk, 107, J. Hallera Street, 80-416 Gdańsk, Poland.
Agata SiwekDepartment of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9, Medyczna Street, 30-688 Kraków, Poland.
Katarzyna StachowiczMaj Institute of Pharmacology, Polish Academy of Sciences, 12, Smętna Street, 31-343 Kraków, Poland.
Bernadeta SzewczykMaj Institute of Pharmacology, Polish Academy of Sciences, 12, Smętna Street, 31-343 Kraków, Poland.
Gabriel NowakDepartment of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9, Medyczna Street, 30-688 Kraków, Poland.
Beata DuszyńskaMaj Institute of Pharmacology, Polish Academy of Sciences, 12, Smętna Street, 31-343 Kraków, Poland.ORCID 0000-0002-1487-3406
Franciszek HeroldDepartment of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097 Warsaw, Poland.
Medical University of Warsaw · PLGdańsk Medical University · PLMaj Institute of Pharmacology · PLJagiellonian University · PL

Funding

Narodowe Centrum Nauki UMO-2013/11/B/NZ7/01638
6 · The paper itself

Abstract

Two series of novel 4-aryl-2H-pyrido[1,2-c]pyrimidine (6a-i) and 4-aryl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine (

Indexed as

PyridinesReceptor, Serotonin, 5-HT1ASerotonin 5-HT1 Receptor AgonistsAnimalsCHO CellsCricetulusHumansPyridinesReceptor, Serotonin, 5-HT1ASerotonin 5-HT1 Receptor Agonistsantidepressantsdrug designdual 5-HT1A/SERT activitypyrido[1,2-c]pyrimidines

Identifiers

PMID33652672
PMCPMC7956643
OpenAlexW3135829023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.