ArticleJournal of functional biomaterials2021
Effects of Process Parameters on Structure and Properties of Melt-Blown Poly(Lactic Acid) Nonwovens for Skin Regeneration.
Article in Journal of functional biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Processing, structure, and properties of PLA/PHA blended melt-blown nonwoven webs for filter media applications.Journal of materials science · 2026Article
- Impact of Polymer Degradation on Cellular Behavior in Tissue Engineering.Bioprinting (Amsterdam, Netherlands) · 2025Article
- Controlled Degradation of PBAT for PBAT/PLA Blend Melt-Blown Nonwovens.Macromolecular rapid communications · 2025Article
- Mechanically reinforced core-shell scaffold with integrated structure and function for accelerated tendon repair.Regenerative biomaterials · 2025Article
- Application of Tendon-Derived Matrix and Carbodiimide Crosslinking Matures the Engineered Tendon-Like Proteome on Meltblown Scaffolds.Journal of tissue engineering and regenerative medicine · 2025Article
- Effect of Polybutylene Succinate Additive in Polylactic Acid Blend Fibers via a Melt-Blown Process.Molecules (Basel, Switzerland) · 2023Article
- Preparation of Self-Curling Melt-Blown Fibers with Crimped Masterbatch (CM) and Its Application for Low-Pressure Air Filtration.Polymers · 2023Article
- Nanofibrous Scaffolds for Diabetic Wound Healing.Pharmaceutics · 2023Review
- Regulation of polylactic acid using irradiation and preparation of PLA-SiORSC advances · 2023Article
- Development and Advantages of Biodegradable PHA Polymers Based on Electrospun PHBV Fibers for Tissue Engineering and Other Biomedical Applications.ACS biomaterials science & engineering · 2021Review
- Surface Modification of Carbon Nanofibers to Improve Their Biocompatibility in Contact with Osteoblast and Chondrocytes Cell Lines.Materials (Basel, Switzerland) · 2021Article
- Composites Composed of Hydrophilic and Hydrophobic Polymers, and Hydroxyapatite Nanoparticles: Synthesis, Characterization, and Study of Their Biocompatible Properties.Journal of functional biomaterials · 2021Article
- 3D Poly(Lactic Acid) Scaffolds Promote Different Behaviors on Endothelial Progenitors and Adipose-Derived Stromal Cells in Comparison With Standard 2D Cultures.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Skin regeneration requires a three-dimensional (3D) scaffold for cell adhesion, growth and proliferation. A type of the scaffold offering a 3D structure is a nonwoven material produced via a melt-blown technique. Process parameters of this technique can be adapted to improve the cellular response. Polylactic acid (PLA) was used to produce a nonwoven scaffold by a melt-blown technique. The key process parameters, i.e., the head and air temperature, were changed in the range from 180-270 °C to obtain eight different materials (MB1-MB8). The relationships between the process parameters, morphology, porosity, thermal properties and the cellular response were explored in this study. The mean fiber diameters ranged from 3 to 120 µm. The average material roughness values were between 47 and 160 µm, whereas the pore diameters ranged from 5 to 400 µm. The calorimetry thermograms revealed a correlation between the temperature parameters and crystallization. The response of keratinocytes and macrophages exhibited a higher cell viability on thicker fibers. The cell-scaffold interaction was observed via SEM after 7 days. This result proved that the features of melt-blown nonwoven scaffolds depended on the processing parameters, such as head temperature and air temperature. Thanks to examinations, the most suitable scaffolds for skin tissue regeneration were selected.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.