Evidence map›Paper›PMID 33651844›Full record

ArticlePloS one2021

Tinnitus and associations with chronic pain: The population-based Tromsø Study (2015-2016).

Jannike H-L Ausland, Bo Engdahl, Bente Oftedal, Ólöf A Steingrímsdóttir, Christopher S Nielsen, Laila A Hopstock, Magnar Johnsen, Oddgeir Friborg, Jan H Rosenvinge, Anne E Eggen and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Review
  9. Article
  10. Article
  11. Association of Vitamin D Deficiency in Patients with Tinnitus with Normal Audiogram.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jannike H-L AuslandDepartment of Environmental Health, Norwegian Institute of Public Health, Skøyen, Oslo, Norway.ORCID 0000-0002-6558-8023
Bo EngdahlDepartment of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Skøyen, Oslo, Norway.
Bente OftedalDepartment of Environmental Health, Norwegian Institute of Public Health, Skøyen, Oslo, Norway.
Ólöf A SteingrímsdóttirDepartment of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Skøyen, Oslo, Norway.
Christopher S NielsenDepartment of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Skøyen, Oslo, Norway.ORCID 0000-0003-0678-331X
Laila A HopstockDepartment of Community Medicine, UiT The Arctic University of Norway, Langnes, Tromsø, Norway.
Magnar JohnsenDepartment of Occupational and Environmental Medicine, University Hospital of North Norway, Tromsø, Norway.
Oddgeir FriborgDepartment of Psychology, UiT The Arctic University of Norway, Langnes, Tromsø, Norway.
Jan H RosenvingeDepartment of Psychology, UiT The Arctic University of Norway, Langnes, Tromsø, Norway.
Anne E EggenDepartment of Community Medicine, UiT The Arctic University of Norway, Langnes, Tromsø, Norway.
Norun H KrogDepartment of Environmental Health, Norwegian Institute of Public Health, Skøyen, Oslo, Norway.ORCID 0000-0002-6883-9609
Norwegian Institute of Public Health · NOUiT The Arctic University of Norway · NOOslo University Hospital · NOUniversity Hospital of North Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tinnitus and pain have many similarities. Both are subjective sensations that may turn chronic, they are often accompanied by hypersensitivity in their respective sensory system, and overlapping brain changes have been observed. Since no population study has examined the empirical association between chronic pain and tinnitus, the present study aimed to explore the relationship in a general adult population. We used data from the seventh survey of the Tromsø Study (2015-2016). Participants (aged ≥40) responded to questions about pain and tinnitus. Using multiple logistic regression, we analysed the adjusted relationship between chronic pain and tinnitus in the full sample (n = 19,039), using several tinnitus definitions ranging from tinnitus >5 minutes within the past 12 months (broadest definition) to at least weekly and highly bothersome tinnitus (strictest definition). We also analysed relationships between number of body regions with pain, pain intensity and bothering, and tinnitus >5 minutes, among participants with chronic pain (n = 11,589). We found an association between chronic pain and tinnitus that was present irrespective of tinnitus definition, but was stronger with more bothersome tinnitus. With chronic pain, the odds of tinnitus >5 minutes was 64% higher, while odds of at least weekly, highly bothersome tinnitus was 144% higher than without chronic pain. Among participants with chronic pain, the number of pain regions was the pain variable most strongly associated with tinnitus >5 minutes (OR = 1.17 (95% CI: 1.14-1.20) for an increase of one region), whereas the other pain variables (intensity and bothering) showed weaker associations. All chronic pain variables had significant interactions with age, with the strongest associations for the youngest individuals (40-54 years). Our findings support the existence of an association between chronic pain and tinnitus and emphasises the importance of examining for comorbid pain in tinnitus patients to provide a more comprehensive treatment of tinnitus.

Indexed as

AdultAgedAged, 80 and overChronic PainComorbidityFemaleHumansIncidenceMaleMiddle AgedNorwayPrevalenceTinnitus

Identifiers

PMID33651844
PMCPMC7924755
OpenAlexW3134375378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.