SynthesisHuman vaccines & immunotherapeutics2021
Infection status and circulating strains of rotaviruses in Chinese children younger than 5-years old from 2011 to 2018: systematic review and meta-analysis.
Synthesis in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Epidemiological characteristics of rotavirus gastroenteritis in China: A systematic review of studies published from 2014 to 2023.Human vaccines & immunotherapeutics · 2026Pooled it
- Prevalence and genetic diversity of rotavirus among children under 5 years of age in China: a meta-analysis.Frontiers in immunology · 2024Pooled it
- Rotavirus outbreaks in China, 1982-2021: a systematic review.Frontiers in public health · 2024Pooled it
- Cost-of-illness of gastroenteritis caused by rotavirus in Chinese children less than 5 years.Human vaccines & immunotherapeutics · 2023Pooled it
- Safety and immunogenicity of inactivated human Rotavirus vaccine in young children and infants: a randomized, placebo-controlled, double-blind, phase I clinical trial.Nature communications · 2026Trial
- Epidemiological, clinical and laboratorial features of rotavirus infection in older children and adults: a multicenter hospital-based study in east China.BMC infectious diseases · 2026Article
- Article
- Incidence rate of rotavirus-associated diarrhea in Pudong New Area, Shanghai, China, during the period 2018-2022.BMC infectious diseases · 2026Article
- Prevalence of group A rotavirus G and P genotypes in children with acute gastroenteritis in China from 2020 to 2021.Archives of virology · 2026Article
- Epidemiological characteristics of Group A rotavirus diarrhea in children under 5 years old in China from 2009 to 2020.BMC infectious diseases · 2025Article
- Diverse processes in rotavirus vaccine development.Human vaccines & immunotherapeutics · 2025Review
- Fecal gut microbiome alterations and its association with lactose intolerance in children with rotavirus infection-related diarrhea.European journal of pediatrics · 2025Article
- [Risk factors and development of a predictive model for myocardial injury in children with rotavirus-induced diarrhea].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Health impact of rotavirus vaccination in China.Human vaccines & immunotherapeutics · 2024Article
- Effectiveness of Lanzhou Lamb Rotavirus Vaccine and RotaTeq Against Hospitalized Rotavirus Infections Among Children During 2020-2023 in Guangdong Province, China: A Test-Negative Case-Control Study.Infectious diseases and therapy · 2024Article
- Immunogenicity of inactivated rotavirus in rhesus monkey, and assessment of immunologic mechanisms.Human vaccines & immunotherapeutics · 2023Article
- Prevalence and genomic analysis of t203-like G9 (G9-VI) rotaviruses circulating in children with gastroenteritis in Beijing, China.Archives of virology · 2023Article
- Article
- Public health impact and cost-effectiveness of rotavirus vaccination in China: Comparison between private market provision and national immunization programs.Human vaccines & immunotherapeutics · 2022Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate rotavirus (RV) disease burden and circulating strains of RV among Chinese children younger than 5-years old who had diarrhea from 2011 to 2018. PubMed, Web of Science, Embase, CNKI and WANFANG databases were systematically searched to identify studies that reported RV prevalence in mainland China. After data extraction, a fixed-effects model or a random-effects model was applied to estimate RV positivity and proportions of G and P types. Statistical analysis was conducted using R software. We initially reviewed 1323 studies, and identified 69 studies that were eligible. The overall proportion of RV gastroenteritis (RVGE) among children under 5-years old who presented with diarrhea and sought medical care was 34.0% (95% CI: 31.3, 36.8), and RV positivity was higher among inpatients (39.7%) than outpatients (23.9%). Western areas of China had the highest proportion of RVGE (42.7%), and RV positivity was highest for children who were 6 months-old to 2 years-old. The most prevalent G types were G3 (26.1%), G9 (17.5%), and G1 (12.8%), the most prevalent P type was P[8] (56.8%) and the most prevalent G-P combination was G9P[8] (20.9%). RV continues to be a main cause of acute gastroenteritis in Chinese children who are younger than 5 years old. Following the introduction of an RV vaccine in 2011, monitoring of the disease burden of RV diarrhea and circulating strains in China remain important for assessments of vaccine efficacy.
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