ArticleAddiction (Abingdon, England)2021
Heroin use cannot be measured adequately with a general population survey.
Article in Addiction (Abingdon, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
74 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between state cannabis laws and opioid outcomes: A systematic review.Drug and alcohol dependence · 2026Pooled it
- A heroin overdose laboratory model: How do escalating doses of diamorphine alter respiratory function in a diamorphine-treated population?Addiction (Abingdon, England) · 2025Trial
- Pilot randomized controlled trial of a hospital-based substance use treatment and recovery team (START) to improve initiation of medication for alcohol or opioid use disorder and linkage to follow-up care.Journal of substance use and addiction treatment · 2023Trial
- Cost-effectiveness of contingency management for methamphetamine use disorder: A model-based analysis.Addiction (Abingdon, England) · 2026Article
- Cost-effectiveness of community-based interventions for reducing opioid overdose and non-overdose deaths: simulation modeling of HEALing Communities Study.Lancet regional health. Americas · 2026Article
- Historical trends in self-reported US heroin initiation.Addiction (Abingdon, England) · 2026Article
- Psychiatric Comorbidities in Substance Use Disorders: Sex-Based Differences in a National Real-World Clinical Sample.The American journal of psychiatry · 2026Article
- Estimating community-level prevalence of opioid use disorder: Extrapolating from Medicaid claims data and other publicly available data sources in Ohio, USA.Addiction (Abingdon, England) · 2026Article
- Association between venlafaxine use and the risk of withdrawal from nonopioid substances: a nationwide, population-based study.Harm reduction journal · 2026Article
- Productivity Losses From Substance Use Disorder in the U.S. in 2023.American journal of preventive medicine · 2026Article
- Use of Illegally Manufactured Fentanyl in the United States: Current Trends.Current addiction reports · 2025Article
- Proactive Bias Mitigation When Using Online Survey Panels for Self-Reported Use of Illicitly Manufactured Fentanyl in the General Adult Population.JAMA health forum · 2025Article
- Monitoring Opioid-Related Social Media Chatter Using Natural Language Processing and Large Language Models: Temporal Analysis.JMIR infodemiology · 2025Article
- Enhancing substance use detection in clinical notes with large language models.Drug and alcohol dependence · 2025Article
- Opioid-use disorder and reported pain after spine surgery: Risk-group patterns in cognitive-appraisal processes in a longitudinal cohort study.North American Spine Society journal · 2025Article
- Enhancing Substance Use Detection in Clinical Notes with Large Language Models.Research square · 2025Article
- Monitoring the opioid epidemic via social media discussions.NPJ digital medicine · 2025Article
- Estimates of Illicit Opioid Use in the US.JAMA health forum · 2025Article
- Synthetic cannabinoid use among noninstitutionalized individuals in the United States, 2021-2023.Drug and alcohol dependence · 2025Article
- Substance use patterns among U.S. adults with HIV: identifying priorities for screening and interventions.AIDS care · 2025Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlobally, heroin and other opioids account for more than half of deaths and years-of-life-lost due to drug use and comprise one of the four major markets for illegal drugs. Having sound estimates of the number of problematic heroin users is fundamental to formulating sound health and criminal justice policies. Researchers and policymakers rely heavily upon general population surveys (GPS), such as the US National Survey on Drug Use and Health (NSDUH), to estimate heroin use, without confronting their limitations. GPS-based estimates are also ubiquitous for cocaine and methamphetamine, so insights pertaining to GPS for estimating heroin use are also relevant for those drug markets. ANALYSIS: Four sources of potential errors in NSDUH are assessed: selective non-response, small sample size, sampling frame omissions and under-reporting. An alternative estimate drawing on a variety of sources including a survey of adult male arrestees is presented and explained. Other approaches to prevalence estimation are discussed.
findingsUnder-reporting and selective non-response in NSDUH are likely to lead to substantial underestimation. Small sample size leads to imprecise estimates and erratic year-to-year fluctuations. The alternative estimate provides credible evidence that NSDUH underestimates the number of frequent heroin users by at least three-quarters and perhaps much more. IMPLICATIONS: GPS, even those as strong as NSDUH, are doomed by their nature to estimate poorly a rare and stigmatized behavior concentrated in a hard-to-track population. Although many European nations avoid reliance upon these surveys, many others follow the US model. Better estimation requires models that draw upon a variety of data sources, including GPS, to provide credible estimates. Recent methodological developments in selected countries can provide guidance. Journals should require researchers to critically assess the soundness of GPS estimates for any stigmatized drug-related behaviors with low prevalence rates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.