SynthesisSurgical endoscopy2021
Surgical treatment of GERD: systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- The SAGES masters program: top 10 seminal articles for laparoscopic fundoplication.Surgical endoscopy · 2025Pooled it
- Magnetic sphincter augmentation in the management of gastro-esophageal reflux disease: a systematic review and meta-analysis.International journal of surgery (London, England) · 2024Pooled it
- Clinical Utility of Anti-reflux Mucosal Intervention for Refractory Gastroesophageal Reflux Disease in Patients With a Hiatal Hernia.DEN open · 2027Article
- Predictive value of preoperative esophagram in postoperative outcomes after antireflux surgery.Surgical endoscopy · 2026Article
- Robotics in Pediatric Surgery: Expanding Indications and Techniques.The Surgical clinics of North America · 2026Review
- Thal versus Nissen fundoplication for the management of pediatric gastroesophageal reflux disease: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Reflections on surgery for hiatal hernia.Updates in surgery · 2026Review
- Robotic Gastrointestinal Surgery Compared to Conventional Approaches: An Umbrella Review of Clinical and Economic Outcomes.Journal of clinical medicine · 2025Review
- Article
- Association between gastroesophageal reflux disease and DMFT index in the PERSIAN Guilan Cohort Study.Scientific reports · 2025Article
- Robot-assisted versus conventional laparoscopic antireflux surgery: a retrospective cohort analysis of perioperative and medium-term outcomes.Journal of robotic surgery · 2025Article
- Quality of life after primary antireflux surgery: an analysis by primary indication.Surgical endoscopy · 2025Article
- Laparoscopic "TOUSSEN" fundoplication for pediatric gastroesophageal reflux disease: a new modified technique gentle as Toupet and solid as Nissen?Pediatric surgery international · 2025Article
- 3D mesh-augmented hiatal hernia repair in patients with GERD: A 3-year single-center experience.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Long-term efficacy and quality of life after antireflux surgery.Surgical endoscopy · 2025Article
- The relationship between intraoperative EndoFLIP™ distensibility index and manometry lower esophageal sphincter basal mean pressure in patients undergoing anti-reflux surgery.Surgical endoscopy · 2025Article
- A retrospective study assessing RefluxStop surgery for gastroesophageal reflux disease: Clinical outcomes in 79 patients from Germany.Surgery open science · 2025Article
- Laparoscopic total (Nissen) versus posterior (Toupet) fundoplication for gastroesophageal reflux disease: a propensity score-matched comparison of the perioperative and 1-year follow-up outcome.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Impact of Toupet fundoplication with bougie on post-operative dysphagia and quality of life.Surgical endoscopy · 2024Article
- A decade of experience with minimally invasive anti-reflux operations: robot vs. LESS.Surgical endoscopy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 10 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastroesophageal reflux disease (GERD) has a high worldwide prevalence in adults and children. There is uncertainty regarding medical versus surgical therapy and different surgical techniques. This review assessed outcomes of antireflux surgery versus medical management of GERD in adults and children, robotic versus laparoscopic fundoplication, complete versus partial fundoplication, and minimal versus maximal dissection in pediatric patients.
methodsPubMed, Embase, and Cochrane databases were searched (2004-2019) to identify randomized control and non-randomized comparative studies. Two independent reviewers screened for eligibility. Random effects meta-analysis was performed on comparative data. Study quality was assessed using the Cochrane Risk of Bias and Newcastle Ottawa Scale.
resultsFrom 1473 records, 105 studies were included. Most had high or uncertain risk of bias. Analysis demonstrated that anti-reflux surgery was associated with superior short-term quality of life compared to PPI (Std mean difference = - 0.51, 95%CI - 0.63, - 0.40, I
conclusionsThe available evidence regarding the optimal treatment of GERD often suffers from high risk of bias. Additional high-quality randomized control trials may further inform surgical decision making in the treatment of GERD.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.