ArticleAbdominal radiology (New York)2021
Evaluation of MR elastography for prediction of lymph node metastasis in prostate cancer.
Article in Abdominal radiology (New York), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Magnetic resonance elastography for prostate cancer: advancing diagnostic accuracy, tumor characterization, and clinical applications.Translational andrology and urology · 2025Review
- Lesion Stiffness Measured by Magnetic Resonance Elastography: A Novel Biomarker for Differentiating Benign, Premalignant and Malignant Prostate Lesions.Diagnostics (Basel, Switzerland) · 2025Article
- Magnetic Resonance Elastography Combined With PI-RADS v2.1 for the Identification of Clinically Significant Prostate Cancer.Journal of magnetic resonance imaging : JMRI · 2025Article
- Quantitative magnetic resonance imaging in prostate cancer: A review of current technology.World journal of radiology · 2024Review
- High-frequency shear wave MR elastography of parotid glands: custom driver design and preliminary results.Scientific reports · 2024Article
- 3D vector MR elastography applications in small organs.Magnetic resonance imaging · 2024Review
- Free-breathing motion corrected magnetic resonance elastography of the abdomen.Quantitative imaging in medicine and surgery · 2024Article
- The role and controversy of pelvic lymph node dissection in prostate cancer treatment: a focused review.World journal of surgical oncology · 2024Review
- Clinical studies of magnetic resonance elastography from 1995 to 2021: Scientometric and visualization analysis based on CiteSpace.Quantitative imaging in medicine and surgery · 2022Article
- The Extracellular Matrix Stiffening: A Trigger of Prostate Cancer Progression and Castration Resistance?Cancers · 2022Review
- Magnetic resonance elastography of the prostate in patients with lower urinary tract symptoms: feasibility of the modified driver at high multi-frequencies.Abdominal radiology (New York) · 2022Article
- Article
- The Advance of Magnetic Resonance Elastography in Tumor Diagnosis.Frontiers in oncology · 2021Review
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Authors and funding
17 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeTo assess the relationship between MRE stiffness of prostate cancer (PCa) and the extent of lymph node metastasis (LNM) in patients with PCa undergoing radical prostatectomy (RP) and extended pelvic lymph node dissection (ePLND). MATERIALS: The local institutional review board approved this retrospective study. We retrospectively analyzed 49 patients, who had undergone MRE, mpMRI and pelvic MRI on a 3.0 T MRI scanner, with histopathological confirmed PCa after RP (from June 2015 to December 2019). For each patient, preoperative clinical data and characteristics of MRE, mpMRI and pelvic MRI were recorded. Independent-samples t test, univariate and multivariate logistic regression analyses were performed. And receiver operating characteristic (ROC) analysis were performed to compare the diagnostic performances of multivariate models with the Briganti 2019 nomogram.
resultsPCa MRE stiffness and maximum diameter were independent predictors of LNM. When PCa MRE stiffness at 60 Hz (odds ratio [OR] = 20.223, P = 0.013) and maximum diameter (OR = 4.575, P = 0.046) were combined, the sensitivity and specificity were 100% and 91.9% to predict LNM. When PCa MRE stiffness at 90 Hz (OR = 7.920, P = 0.013) and maximum diameter (OR = 2.810, P = 0.045) were combined, the sensitivity and specificity were 100% and 86.5% to predict LNM. The areas under curves (AUCs) of the combinations were higher than the AUC of the Briganti 2019 nomogram (0.982 vs. 0.904, P = 0.040 [60 Hz]; 0.975 vs. 0.904, P = 0.060 [90 Hz], respectively).
conclusionsMRE-based assessment of PCa stiffness may be useful for predicting LNM of PCa preoperatively and noninvasively.
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