ArticleeLife2021
Integrative frontal-parietal dynamics supporting cognitive control.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06276400 (Lateral Prefrontal Organization in Emotion), which is not on this map. Cited by 56 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Lateral Prefrontal Organization in Emotion: Representational and Causal Mechanism - Duration Difference Estimation
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Neural mechanism of Shugan Jieyu combined with zolpidem in insomnia disorder with depressive symptoms: evidence from event-related potentials in Go/No-Go and psychomotor vigilance task.BMC psychiatry · 2026Trial
- Trial
- Hierarchical disruption of lateral prefrontal cortex gradients in cognitive aging.GeroScience · 2026Article
- Biological factors contributing to divergent cortical abnormalities in adolescent and adult psychiatric disorders.Translational psychiatry · 2026Article
- Functional Connectome Predicts Cognition and Links White Matter Hyperintensity Burden to Cognitive Impairment Across the Vascular Cognitive Impairment Continuum.Brain sciences · 2026Article
- Lonely individuals have a more negative perception of their bodies: The mediating role of self-cognition and social perception brain network connectivity.Cognitive, affective & behavioral neuroscience · 2026Article
- Latent brain state dynamics predict early amyloid accumulation and cognitive impairment.bioRxiv : the preprint server for biology · 2026Article
- Neurocomputational modeling of rule abstraction and memorization during probabilistic stimulus-reward learning.iScience · 2026Article
- Altered temporal organization of neural response dynamics during attention processing differentiates ADHD subtypes in children.NeuroImage. Clinical · 2026Article
- Avoidance habit learning in adolescents and young women with anorexia nervosa: an fMRI study.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Effects of Progressive Aerobic Training on Executive-Reward Network Connectivity and Symptoms of Internet Gaming Disorder: Randomized Controlled Trial.JMIR serious games · 2025Article
- Mapping content and dynamics in the stream of consciousness through latent brain state analysis.iScience · 2025Article
- Effects of Sanda Sports Training on Cognitive-Motor Control Based on EEG and Heart Rate Sensors: A Coupled ERP and HRV Analysis.Sensors (Basel, Switzerland) · 2025Article
- Article
- Deep Learning of Brain-Behavior Dimensions Identifies Transdiagnostic Biotypes in Youth with ADHD and Anxiety Disorders.bioRxiv : the preprint server for biology · 2025Article
- The Impact of Chinese Martial Arts Sanda Training on Cognitive Control and ERP: An EEG Sensors Study.Sensors (Basel, Switzerland) · 2025Article
- Preparatory attentional templates in prefrontal and sensory cortex encode target-associated information.eLife · 2025Article
- Individual-specific subspace of altered functional connectivity predicts clinical symptoms in Internet gaming disorder.Journal of behavioral addictions · 2025Article
- Altered dynamic reconfiguration of brain functional networks during gaming and deprivation in individuals with internet gaming disorder.Journal of behavioral addictions · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Coordinating among the demands of the external environment and internal plans requires cognitive control supported by a fronto-parietal control network (FPCN). Evidence suggests that multiple control systems span the FPCN whose operations are poorly understood. Previously (Nee and D'Esposito, 2016; 2017), we detailed frontal dynamics that support control processing, but left open their role in broader cortical function. Here, I show that the FPCN consists of an external/present-oriented to internal/future-oriented cortical gradient extending outwardly from sensory-motor cortices. Areas at the ends of this gradient act in a segregative manner, exciting areas at the same level, but suppressing areas at different levels. By contrast, areas in the middle of the gradient excite areas at all levels, promoting integration of control processing. Individual differences in integrative dynamics predict higher level cognitive ability and amenability to neuromodulation. These data suggest that an intermediary zone within the FPCN underlies integrative processing that supports cognitive control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.