ArticlePhysiological reports2021
Effect of the order of concurrent training combined with resistance and high-intensity interval exercise on mTOR signaling and glycolytic metabolism in mouse skeletal muscle.
Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Hematopoietic progenitor cells (HPCs) mobilization following high-intensity interval exercise in cancer patients undergoing bone marrow transplantation: preliminary results from a randomized controlled trial.Stem cell research & therapy · 2026Trial
- Ovarian hormone loss modifies the nucleic acid cargo of circulating extracellular vesicles and skeletal muscle metabolism after acute exercise in rats.Experimental physiology · 2026Article
- Concurrent HIIT and Resistance Training for Musculoskeletal Function: A Systematic Review of Neuromuscular, Morphological, and Performance Adaptations.Life (Basel, Switzerland) · 2026Review
- Effect of Muscle Contraction Under Caloric Restriction on Irisin and FGF21 Secretion in Mice.Physiological research · 2025Article
- Combined effects of mechanical overload and high-intensity interval training on skeletal muscle hypertrophy in male mice.Physiological reports · 2025Article
- High-Intensity Aerobic Exercise Prevents Angiotensin II-Induced Muscle Atrophy.International neurourology journal · 2025Article
- The effects, mechanisms, and influencing factors of concurrent strength and endurance training with different sequences: a semi-systematic review.Frontiers in sports and active living · 2025Review
- A Mango Leaf Extract (ZynamiteNutrients · 2023Article
- Physiological profile comparison between high intensity functional training, endurance and power athletes.European journal of applied physiology · 2022Article
- Effect of lactate administration on mouse skeletal muscle under calorie restriction.Current research in physiology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Athletes train to improve strength and endurance to demonstrate maximum performance during competitions. Training methods vary but most focus on strength, endurance, or both. Concurrent training is a combination of two different modes of training. In this study, we combined resistance exercise (RE) and high-intensity interval exercise (HIIE) to investigate the influence of the order of the concurrent training on signal molecules on hypertrophy and glycolysis in the skeletal muscle. The phosphorylation levels of mechanistic target of rapamycin (mTOR) signals, p70 S6 kinase (p70S6 K), ribosomal protein S6 (S6), and glycogen synthase kinase beta (GSK-3β) were significantly increased in the HIIE first group compared with the control group. The combined training course did not affect the glycogen content and expression levels of proteins concerning glycolytic and metabolic capacity, suggesting that a combination of HIIE and RE on the same day, with HIIE prior to RE, improves hypertrophy response and glycolysis enhancement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.