ArticleHuman brain mapping2021
Test-retest reliability of approach-avoidance conflict decision-making during functional magnetic resonance imaging in healthy adults.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Prediction of generalized anxiety disorder treatment outcomes with neurobehavioral responses to approach-avoidance conflict: a randomized clinical trial.Translational psychiatry · 2025Trial
- Attenuated learning rates for negative outcomes in substance use disorders: A replication and extension of prior longitudinal computational modeling results.Drug and alcohol dependence · 2026Article
- Social approach-avoidance conflict: Behavioural, emotional, and neural correlates along a depression-social anxiety spectrum.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Approach-avoidance conflict recruits lateral frontoparietal and cinguloinsular networks in a predator-prey game setting.Cognitive, affective & behavioral neuroscience · 2025Article
- Neural correlates of approach-avoidance tendencies toward physical activity and sedentary stimuli: An MRI study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Interindividual differences in Pavlovian influence on learning are consistent.Royal Society open science · 2023Article
- Computational perspectives on human fear and anxiety.Neuroscience and biobehavioral reviews · 2023Review
- Measuring maladaptive avoidance: from animal models to clinical anxiety.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- Long-term stability of computational parameters during approach-avoidance conflict in a transdiagnostic psychiatric patient sample.Scientific reports · 2021Article
- Test-retest reliability of approach-avoidance conflict decision-making during functional magnetic resonance imaging in healthy adults.Human brain mapping · 2021Article
- Why Stuttering Occurs: The Role of Cognitive Conflict and Control.Topics in language disordersArticle
- Striatal reactivity during emotion and reward relates to approach-avoidance conflict behaviour and is altered in adults with anxiety or depression.Journal of psychiatry & neuroscience : JPNArticle
- Elevated decision uncertainty and reduced avoidance drives in depression, anxiety and substance use disorders during approach-avoidance conflict: a replication study.Journal of psychiatry & neuroscience : JPNArticle
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Authors and funding
7 authors.
Funding
Abstract
Neural and behavioral mechanisms during approach-avoidance conflict decision-making are relevant across various psychiatric disorders, particularly anxiety disorders. Studies using approach-avoidance conflict paradigms in healthy adults have identified preliminary neural mechanisms, but findings must be replicated and demonstrated as reliable before further application. This study sought to replicate previous findings and examine test-retest reliability of behavioral (approach behavior, reaction time) and neural (regions of interest [ROIs]) responses during an approach-avoidance conflict task conducted during functional magnetic resonance imaging (fMRI). Thirty healthy adults completed an approach-avoidance conflict task during fMRI on two occasions (mean interval: 17 days; range: 11-32). Effects of task condition during three task phases (decision-making, affective outcome and monetary reward) and intraclass correlation coefficients (ICCs) were calculated across time points. Results replicated that approach behavior was modulated by conflict during decision-making. ROI activations were replicated such that dorsal anterior cingulate cortex (dACC) was modulated by conflict during decision-making, and dACC, striatum, and anterior insula were modulated by valence during affective outcomes (p's <.0083). Approach behavior during conflict demonstrated excellent reliability (ICCs ≥.77). Activation of dACC during conflict decision-making and anterior insula during negative outcomes demonstrated fair reliability (ICCs = .51 and .54), and dACC and striatum activation demonstrated good reliability during negative outcomes (ICCs = .63 and .69). Two additional ROIs (amygdala, left dorsolateral prefrontal cortex) showed good reliability during negative outcomes (ICCs ≥.60). These results characterize several specific behavioral and neuroimaging responses that are replicable and sufficiently reliable during approach-avoidance conflict decision-making to support future utility.
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