Evidence map›Paper›PMID 33650759›Full record

ReviewJournal of cellular and molecular medicine2021

Gynaecological cancers and their cell lines.

Kristijan Skok, Lidija Gradišnik, Uroš Maver, Nejc Kozar, Monika Sobočan, Iztok Takač, Darja Arko, Rajko Kavalar

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Ring-fused chlorin-enhanced photodynamic therapy for effective cell death induction in endometrial cancer.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Gynaecological cancers and their cell lines.Journal of cellular and molecular medicine · 2021
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kristijan SkokDepartment of pathology, General Hospital Graz II, Graz, Austria.ORCID 0000-0002-3027-8164
Lidija GradišnikInstitute of Biomedical Sciences, Faculty of Medicine, University of Maribor, Maribor, Slovenia.ORCID 0000-0003-3492-0297
Uroš MaverInstitute of Biomedical Sciences, Faculty of Medicine, University of Maribor, Maribor, Slovenia.ORCID 0000-0002-2237-3786
Nejc KozarDivision of Gynecology and Perinatology, University Medical Center Maribor, Maribor, Slovenia.ORCID 0000-0003-0934-5024
Monika SobočanDivision of Gynecology and Perinatology, University Medical Center Maribor, Maribor, Slovenia.ORCID 0000-0003-1384-9487
Iztok TakačDivision of Gynecology and Perinatology, University Medical Center Maribor, Maribor, Slovenia.ORCID 0000-0003-4599-7265
Darja ArkoDivision of Gynecology and Perinatology, University Medical Center Maribor, Maribor, Slovenia.
Rajko KavalarFaculty of Medicine, University of Maribor, Maribor, Slovenia.ORCID 0000-0002-3958-5371

Funding

Javna Agencija za Raziskovalno Dejavnost RS I0-0029Javna Agencija za Raziskovalno Dejavnost RS J3-9272Javna Agencija za Raziskovalno Dejavnost RS L4-1843Javna Agencija za Raziskovalno Dejavnost RS P3-0036Univerzitetni Klinični Center Maribor IRP 2018/01-10Univerzitetni Klinični Center Maribor IRP 2018/01-19
6 · The paper itself

Abstract

Cell lines are widely used for various research purposes including cancer and drug research. Recently, there have been studies that pointed to discrepancies in the literature and usage of cell lines. That is why we have prepared a comprehensive overview of the most common gynaecological cancer cell lines, their literature, a list of currently available cell lines, and new findings compared with the original studies. A literature review was conducted via MEDLINE, PubMed and ScienceDirect for reviews in the last 5 years to identify research and other studies related to gynaecological cancer cell lines. We present an overview of the current literature with reference to the original studies and pointed to certain inconsistencies in the literature. The adherence to culturing rulesets and the international guidelines helps in minimizing replication failure between institutions. Evidence from the latest research suggests that despite certain drawbacks, variations of cancer cell lines can also be useful in regard to a more diverse genomic landscape.

Indexed as

Cell Culture TechniquesCell Line, TumorFemaleGenital Neoplasms, FemaleHumansbreast neoplasmcell linecervix cancerendometrial neoplasmsgynaecologyin vitro techniquespathologytumour cell line

Identifiers

PMID33650759
PMCPMC8051715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.