ArticleJournal of cardiovascular electrophysiology2021
Atrial electrophysiological characteristics of aging.
Article in Journal of cardiovascular electrophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Risk factors of atrial fibrillation progression in patients with congenital heart disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Impact of vagus nerve cross-sectional area on electrocardiogram parameters in community-dwelling older adults: The YAHABA study.PloS one · 2026Article
- Nomogram for severe low-voltage areas prediction in older patients with paroxysmal atrial fibrillation: a retrospective cohort study.BMC geriatrics · 2025Article
- Cellular and molecular mechanisms underlying cardiovascular aging.Cellular & molecular biology letters · 2025Review
- The role of cellular senescence in cardiovascular disease.Cell death discovery · 2025Review
- Time's imprint on the left atrium: aging and atrial myopathy.The journal of cardiovascular aging · 2025Article
- High-Density and Resolution Epicardial Mapping of the Atria: Translational Research with Clinical Impact.Journal of clinical medicine · 2024Review
- Unipolar atrial electrogram morphology is affected by age: evidence from high-resolution epicardial mapping.Annals of medicine · 2023Article
- Does conduction heterogeneity determine the supervulnerable period after atrial fibrillation?Medical & biological engineering & computing · 2023Article
- Review
- Reduction of Conduction Velocity in Patients with Atrial Fibrillation.Journal of clinical medicine · 2021Article
- Atrial electrophysiological characteristics of aging.Journal of cardiovascular electrophysiology · 2021Article
Corrections and comments
- Commented on by
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAdvancing age is a known risk factor for developing atrial fibrillation (AF), yet it is unknown which electrophysiological changes contribute to this increased susceptibility. The goal of this study is to investigate conduction disturbances and unipolar voltages (UV) related to aging.
methodsWe included 216 patients (182 male, age: 36-83 years) without a history of AF undergoing elective coronary artery bypass surgery. Five seconds of sinus rhythm were recorded intraoperatively at the right atrium (RA), Bachmann's bundle (BB), the left atrium and the pulmonary vein area (PVA). Conduction delay (CD), -block (CB), -velocity (CV), length of longest CB lines and UV were assessed in all regions.
resultsWith aging, increasing conduction disturbances were found, particularly at RA and BB (RA: longest CB line r
conclusionsAging is accompanied by an increase in conduction disturbances during sinus rhythm and a higher prevalence of low UV areas, particularly at BB and in the RA. These electrophysiological alterations could in part explain the increasing susceptibility to AF development associated with aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.