Evidence map›Paper›PMID 33650552›Full record

ArticleJournal of synchrotron radiation2021

Perspectives for microbeam irradiation at the SYRMEP beamline.

Elisabeth Schültke, Stefan Fiedler, Ralf Hendrik Menk, Felix Jaekel, Diego Dreossi, Katia Casarin, Giuliana Tromba, Stefan Bartzsch, Stephan Kriesen, Guido Hildebrandt and 1 more

Abstract read
In one paragraph

Article in Journal of synchrotron radiation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elisabeth SchültkeDepartment of Radiooncology, Rostock University Medical Center, Südring 75, 18059 Rostock, Germany.
Stefan FiedlerEuropean Molecular Biology Laboratory, Notkestrasse 85, 22607 Hamburg, Germany.
Ralf Hendrik MenkElettra-Sincrotrone Trieste, Strada Statale 14, Trieste 34149, Italy.ORCID 0000-0003-2676-8336
Felix JaekelDepartment of Radiooncology, Rostock University Medical Center, Südring 75, 18059 Rostock, Germany.
Diego DreossiElettra-Sincrotrone Trieste, Strada Statale 14, Trieste 34149, Italy.
Katia CasarinElettra-Sincrotrone Trieste, Strada Statale 14, Trieste 34149, Italy.
Giuliana TrombaElettra-Sincrotrone Trieste, Strada Statale 14, Trieste 34149, Italy.
Stefan BartzschDepartment of Radiooncology, Technical University Munich, Munich, Germany.
Stephan KriesenDepartment of Radiooncology, Rostock University Medical Center, Südring 75, 18059 Rostock, Germany.
Guido HildebrandtDepartment of Radiooncology, Rostock University Medical Center, Südring 75, 18059 Rostock, Germany.
Fulvia ArfelliTrieste Section, Istituto Nazionale Fisica Nucleare (INFN), Trieste, Italy.

Funding

Deutsche Forschungsgemeinschaft SCHU 2589/7-1.
6 · The paper itself

Abstract

It has been shown previously both in vitro and in vivo that microbeam irradiation (MBI) can control malignant tumour cells more effectively than the clinically established concepts of broad beam irradiation. With the aim to extend the international capacity for microbeam research, the first MBI experiment at the biomedical beamline SYRMEP of the Italian synchrotron facility ELETTRA has been conducted. Using a multislit collimator produced by the company TECOMET, arrays of quasi-parallel microbeams were successfully generated with a beam width of 50 µm and a centre-to-centre distance of 400 µm. Murine melanoma cell cultures were irradiated with a target dose of approximately 65 Gy at a mean photon energy of ∼30 keV with a dose rate of 70 Gy s

Indexed as

PhotonsSynchrotronsAnimalsMiceMonte Carlo Methodmicrobeammicrobeam irradiationmurine melanoma cellsradiotherapy

Identifiers

PMID33650552
PMCPMC7941286

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.