ArticleeLife2021
Genomic epidemiology of COVID-19 in care homes in the east of England.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Review
- Genomic epidemiology of SARS-CoV-2 in Norfolk, UK, March 2020-December 2022.Microbial genomics · 2025Article
- Article
- Epidemiological inference at the threshold of data availability: an influenza A(H1N2)v spillover event in the United Kingdom.Journal of the Royal Society, Interface · 2024Article
- Changing genomic epidemiology of COVID-19 in long-term care facilities during the 2020-2022 pandemic, Washington State.BMC public health · 2024Article
- Sequencing analysis of SARS-CoV-2 cases in Slovenian long-term care facilities to support outbreak control.Frontiers in public health · 2024Article
- Coronavirus disease 2019 (COVID-19) outbreak on an in-patient medical unit associated with unrecognized exposures in common areas-Epidemiological and whole-genome sequencing investigation.Infection control and hospital epidemiology · 2023Article
- Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes.The Journal of hospital infection · 2023Article
- Transmission of Carbapenem-Resistant Klebsiella pneumoniae in US Hospitals.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Article
- COVID salivary diagnostics: A comparative technical study.Journal of medical virology · 2022Article
- The need for linked genomic surveillance of SARS-CoV-2.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022Article
- Social Distancing and Isolation Strategies to Prevent and Control the Transmission of COVID-19 and Other Infectious Diseases in Care Homes for Older People: An International Review.International journal of environmental research and public health · 2022Review
- A2B-COVID: A Tool for Rapidly Evaluating Potential SARS-CoV-2 Transmission Events.Molecular biology and evolution · 2022Article
- Characterising within-hospitalSARS-CoV-2 transmission events using epidemiological and viral genomic data across two pandemic waves.Nature communications · 2022Article
- The role of viral genomics in understanding COVID-19 outbreaks in long-term care facilities.The Lancet. Microbe · 2022Review
- Limited genomic reconstruction of SARS-CoV-2 transmission history within local epidemiological clusters.Virus evolution · 2022Article
- Outbreak of SARS-CoV-2 infection in a long-term care facility after COVID-19 BNT162b2 mRNA vaccination.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
38 authors at 6 institutions in 1 country.
Funding
Abstract
COVID-19 poses a major challenge to care homes, as SARS-CoV-2 is readily transmitted and causes disproportionately severe disease in older people. Here, 1167 residents from 337 care homes were identified from a dataset of 6600 COVID-19 cases from the East of England. Older age and being a care home resident were associated with increased mortality. SARS-CoV-2 genomes were available for 700 residents from 292 care homes. By integrating genomic and temporal data, 409 viral clusters within the 292 homes were identified, indicating two different patterns - outbreaks among care home residents and independent introductions with limited onward transmission. Approximately 70% of residents in the genomic analysis were admitted to hospital during the study, providing extensive opportunities for transmission between care homes and hospitals. Limiting viral transmission within care homes should be a key target for infection control to reduce COVID-19 mortality in this population.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.