Evidence map›Paper›PMID 33650474›Full record

ArticleInfection control and hospital epidemiology2021

Concordance of antibiotic prescribing with the American Dental Association acute oral infection guidelines within Veterans' Affairs (VA) dentistry.

Daniel B Carlsen, Michael J Durkin, Gretchen Gibson, M Marianne Jurasic, Ursula Patel, Linda Poggensee, Margaret A Fitzpatrick, Kelly Echevarria, Jessina McGregor, Charlesnika T Evans and 1 more

Open access · greenAbstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  8. Infection control and hospital epidemiology · 2023
    Article
  9. Article
  10. Article
  11. Opportunities for penicillin allergy evaluation in dental clinics.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Daniel B CarlsenPharmacy Department, Edward Hines Jr, Veterans' Affairs (VA) Hospital, Hines, Illinois.
Michael J DurkinWashington University School of Medicine, St Louis, Missouri.
Gretchen GibsonOral Health Quality Group, Veterans' Health Care System of the Ozarks, Fayetteville, Arkansas.
M Marianne JurasicVA Center for Healthcare Organization and Implementation Research, Edith Nourse Rogers Memorial Veterans' Hospital, Bedford, Massachusetts.
Ursula PatelPharmacy Department, Edward Hines Jr, Veterans' Affairs (VA) Hospital, Hines, Illinois.
Linda PoggenseeCenter of Innovation for Complex Chronic Healthcare, Edward Hines Jr, VA Hospital, Hines, Illinois.
Margaret A FitzpatrickCenter of Innovation for Complex Chronic Healthcare, Edward Hines Jr, VA Hospital, Hines, Illinois.
Kelly EchevarriaVA Pharmacy Benefits Management Services, San Antonio, Texas.
Jessina McGregorCollege of Pharmacy, Oregon State University, Corvallis, Oregon.
Charlesnika T EvansCenter of Innovation for Complex Chronic Healthcare, Edward Hines Jr, VA Hospital, Hines, Illinois.
Katie J SudaCenter for Health Equity Research and Promotion, VA Pittsburgh Health Care System, Pittsburgh, Pennsylvania.
Edward Hines, Jr. VA Hospital · USVeterans Health Administration · USEdith Nourse Rogers Memorial Veterans Hospital · USLoyola University Chicago · USOregon Health & Science University · USUniversity of Pittsburgh · USVeterans Health Care System of the Ozarks · USWashington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Using Implementation Science and Informatics to Develop and Pilot Test Antibiotic Stewardship Clinical Decision SupportK23DE029514 · NIDCR · WASHINGTON UNIVERSITY · PI DURKIN, MICHAEL JOSEPH · 2021 to 2025
$632k
Improving Veteran Health by Increasing Dental Stewardship of Antibiotics and OpioidsI01HX002452 · VA · EDWARD HINES JR VA HOSPITAL · PI SUDA, KJ · 2018 to 2021
–
HSR&D Research Career Scientist AwardIK6HX003156 · VA · EDWARD HINES JR VA HOSPITAL · PI EVANS, CHARLESNIKA T · 2020 to 2025
–
HSRD VA I01 HX002452HSRD VA IK6 HX003156NCATS NIH HHS KL2 TR002346NCEZID CDC HHS U54 CK000609NIAID NIH HHS L30 AI133778NIDCR NIH HHS K23 DE029514
6 · The paper itself

Abstract

objectiveUnited States dentists prescribe 10% of all outpatient antibiotics. Assessing appropriateness of antibiotic prescribing has been challenging due to a lack of guidelines for oral infections. In 2019, the American Dental Association (ADA) published clinical practice guidelines (CPG) on the management of acute oral infections. Our objective was to describe baseline national antibiotic prescribing for acute oral infections prior to the release of the ADA CPG and to identify patient-level variables associated with an antibiotic prescription.

designCross-sectional analysis.

methodsWe performed an analysis of national VA data from January 1, 2017, to December 31, 2017. We identified cases of acute oral infections using International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM) codes. Antibiotics prescribed by a dentist within ±7 days of a visit were included. Multivariable logistic regression identified patient-level variables associated with an antibiotic prescription.

resultsOf the 470,039 VA dental visits with oral infections coded, 12% of patient visits with irreversible pulpitis, 17% with apical periodontitis, and 28% with acute apical abscess received antibiotics. Although the median days' supply was 7, prolonged use of antibiotics was frequent (≥8 days, 42%-49%). Patients with high-risk cardiac conditions, prosthetic joints, and endodontic, implant, and oral and maxillofacial surgery dental procedures were more likely to receive antibiotics.

conclusionsMost treatments of irreversible pulpitis and apical periodontitis cases were concordant with new ADA guidelines. However, in cases where antibiotics were prescribed, prolonged antibiotic courses >7 days were frequent. These findings demonstrate opportunities for the new ADA guidelines to standardize and improve dental prescribing practices.

Indexed as

Anti-Bacterial AgentsVeteransAmerican Dental AssociationCross-Sectional StudiesDentistryHumansPractice Patterns, Dentists'United StatesAnti-Bacterial Agents

Identifiers

PMID33650474
PMCPMC8410877
OpenAlexW3134513219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.