ArticleAllergy2021
Impact of anxiety, stress and depression related to COVID-19 pandemic on the course of hereditary angioedema with C1-inhibitor deficiency.
Article in Allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Associations of Sleep Quality and Perceived Stress with Skin, Scalp, and Hair Health Among 1,017 Chinese Women: A Cross-Sectional Observational Study.Clinical, cosmetic and investigational dermatology · 2026Article
- Behavioural withdrawal during an acute stress test as a marker of psychobiological vulnerability in hereditary angioedema.Frontiers in immunology · 2026Article
- Functional physiological, psychological, and biochemical reactivity to socially evaluated cold pressor test in hereditary angioedema patients (FRoSEn).Frontiers in immunology · 2025Observational
- Ecological momentary assessments for patients with hereditary angioedema: a feasibility and acceptability controlled study.Frontiers in digital health · 2025Article
- Patient-physician interactions in hereditary angioedema-Key learnings from the coronavirus disease 2019 pandemic.Clinical and translational allergy · 2023Review
- Immunogenicity and Safety of Anti-SARS-CoV-2 mRNA Vaccines in a Cohort of Patients with Hereditary Angioedema.Vaccines · 2023Article
- Positive perception of COVID-19 vaccination in HAE: No significant impact of vaccination on disease course.Allergy and asthma proceedings · 2022Article
- COVID-19 triggers attacks in HAE patients without worsening disease outcome.The journal of allergy and clinical immunology. In practice · 2022Article
- Impact of mental health on disease activity in mastocytosis during COVID-19 pandemic.Allergology international : official journal of the Japanese Society of Allergology · 2022Article
- Global perceptions of the current and future impacts of COVID-19 on hereditary angioedema management.Allergy and asthma proceedings · 2022Article
- Depression, Anxiety, Stress, and Their Associations With Quality of Life in a Nationwide Sample of Psychiatrists in China During the COVID-19 Pandemic.Frontiers in psychology · 2022Article
- Validation of diagnostic and predictive biomarkers for hereditary angioedema via plasma N-glycomics.Clinical and translational allergy · 2021Article
- Recent advances and developments in COVID-19 in the context of allergic diseases.Clinical and translational allergy · 2021Article
- Effect of COVID-19 on hereditary angioedema activity and quality of life.Allergy and asthma proceedings · 2021Article
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHereditary angioedema (HAE) attacks can be provoked with psychological factors. The aim of this study was to assess the effects of anxiety, depression and stress related to COVID-19 pandemic on disease activity of HAE patients during the quarantine period (QP) and the return to normal period (RTNP).
methodsThis study was conducted between March 2020 and September 2020 in four allergy centres. Demographic, clinical features and mental health status were evaluated in QP (from March to the beginning of June) and RTNP (from June to the beginning of September) applied by the government. The 10-point visual analogue scale (VAS10) was used to define the severity of HAE attacks. Depression, Anxiety and Stress Scales-21 (DASS-21) and Fear of COVID-19 (FC-19) scale were performed to assess mental health status.
results139 HAE patients were included in the study. In QP, median attack numbers and median VAS10 scores were 5 (min-max: 0-45) and 6 (min-max: 0-10), respectively. HAE attack numbers, DASS-21 stress, anxiety, depression and total DASS-21 scores, and FC-19 scores were higher in QP than RTNP (p = 0.001, p < 0.001, p = 0.001, p < 0.001, p < 0.001, p < 0.001, respectively). However, there was no difference in attack severity scores between the two periods (p > 0.05).
conclusionsThis study revealed that the restriction measures during COVID-19 outbreak cause an increase in the number of HAE attacks in relation to anxiety, depression, stress and fear of COVID-19 pandemic. Therefore, it is important to provide psychological support to HAE patients during the pandemic.
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