Evidence map›Paper›PMID 33649806›Full record

ReviewInternational journal of oncology2021

Clinical crosstalk between microRNAs and gastric cancer (Review).

Jing Ouyang, Zhizhong Xie, Xiaoyong Lei, Guotao Tang, Runliang Gan, Xiaoyan Yang

Open access · bronzeAbstract readReview
In one paragraph

Review in International journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. World journal of gastrointestinal oncology · 2025
    Article
  3. Article
  4. Article
  5. The miR-155-5p/Translational cancer research · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jing OuyangInstitute of Pharmacy and Pharmacology, University of South China, Hengyang, Hunan 421001, P.R. China.
Zhizhong XieInstitute of Pharmacy and Pharmacology, University of South China, Hengyang, Hunan 421001, P.R. China.
Xiaoyong LeiInstitute of Pharmacy and Pharmacology, University of South China, Hengyang, Hunan 421001, P.R. China.
Guotao TangInstitute of Pharmacy and Pharmacology, University of South China, Hengyang, Hunan 421001, P.R. China.
Runliang GanCancer Research Institute, Hengyang Medical College, University of South China, Hengyang, Hunan 421001, P.R. China.
Xiaoyan YangInstitute of Pharmacy and Pharmacology, University of South China, Hengyang, Hunan 421001, P.R. China.
University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, there were over 1 million new gastric cancer (GC) patients in 2018 and GC has become the sixth most common cancer worldwide. GC caused 783,000 deaths worldwide in 2018, making it the third most deadly cancer type. miRNAs are short (~22 nucleotides in length) non‑coding RNA molecules, which can regulate gene expression passively at a post‑transcriptional level. There are more and more in‑depth studies on miRNAs. There are numerous conclusive evidences that there is an inseparable link between miRNAs and GC. miRNAs can affect the entire process of GC, including the oncogenesis, development, diagnosis, treatment and prognosis of GC. Although many miRNAs have been linked to GC, few can be applied to clinical practice. This review takes the clinical changes of GC as a clue and summarizes the miRNAs related to GC that have confirmed the mechanism of action in the past three years. Through in‑depth study and understanding of the mechanism of those miRNAs, we predict their possible clinical uses, and suggest some new insights to overcome GC.

Indexed as

Gene Expression ProfilingGene Expression Regulation, NeoplasticBiomarkers, TumorHumansMicroRNAsPrognosisStomach NeoplasmsBiomarkers, TumorMicroRNAsclinical applicationsgastric cancermicroRNAs

Identifiers

PMID33649806
PMCPMC7895535
OpenAlexW3128610255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.