Evidence map›Paper›PMID 33649802›Full record

ArticleInternational journal of molecular medicine2021

Iron overload in aging

Martina Pauk, Vera Kufner, Viktorija Rumenovic, Ivo Dumic-Cule, Vladimir Farkas, Milan Milosevic, Tatjana Bordukalo-Niksic, Slobodan Vukicevic

Open access · bronzeAbstract read
In one paragraph

Article in International journal of molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Targeting macro- and micro-nutrient regulation of HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  2. Review
  3. The Influence of BMP6 on Serotonin and Glucose Metabolism.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Martina PaukLaboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Vera KufnerLaboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Viktorija RumenovicLaboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Ivo Dumic-CuleLaboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Vladimir FarkasMolecular Biology Department, Rudjer Boskovic Institute, HR‑10000 Zagreb, Croatia.
Milan MilosevicAndrija Stampar School of Public Health, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Tatjana Bordukalo-NiksicLaboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Slobodan VukicevicLaboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
University of Zagreb · HRRuđer Bošković Institute · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between hemochromatosis and diabetes has been well established, as excessive iron deposition has been reported to result in impaired function of the endocrine and exocrine pancreas. Therefore, the objective of the present study was to analyze the effects of iron accumulation on the pancreata and glucose homeostasis in a bone morphogenetic protein 6‑knockout (

Indexed as

Acinar CellsAnimalsBlood GlucoseBone Morphogenetic Protein 6Diabetes MellitusDisease Models, AnimalFibrosisFluorodeoxyglucose F18GlucoseHemochromatosisIronIron OverloadMiceMice, Inbred C57BLMice, KnockoutPancreasBlood GlucoseBmp6 protein, mouseBone Morphogenetic Protein 6Fluorodeoxyglucose F18GlucoseIronbone morphogenetic protein 6diabetesglucose homeostasisiron metabolismpancreas

Identifiers

PMID33649802
PMCPMC7910010
OpenAlexW3132130312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.