Evidence map›Paper›PMID 33649730›Full record

ArticleReports of biochemistry & molecular biology2020

Maryam Salimi, Abolfazl Shirazi, Mohsen Norouzian, Ameneh Jafari, Haleh Edalatkhah, Maryam Mehravar, Mohammad Majidi, Mohammad Mahdi Mehrazar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reports of biochemistry & molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Maryam SalimiDepartment of Biology and Anatomical Sciences, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abolfazl ShiraziReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Mohsen NorouzianReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Ameneh JafariStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Haleh EdalatkhahReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Maryam MehravarReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Mohammad MajidiFood and Drug Laboratory Research Center, Food and Drug Organization, MOH & ME, Tehran, Iran.
Mohammad Mahdi MehrazarReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Shahid Beheshti University of Medical Sciences · IRAcademic Center for Education, Culture and Research · IRBiotechnology Research Center · IRIran Nanohealth Committee Food and Drug Organization · IRShahrekord University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, the efficient production of chimeric mice and their survival are still challenging. Recent researches have indicated that preimplantation embryo culture media and manipulation lead to abnormal methylation of histone in the

methodsMouse 129/Sv embryonic stem cells (mESCs) expressing the green fluorescent protein (mESCs-GFP) were injected into the perivitelline space of 2.5 days post-coitis (dpc) embryos (C57BL/6) using a micromanipulator. H3K4 and H3K9 methylation, and H19 and

resultsHistone H3 trimethylation in H3K4 and H3K9 in chimeric blastocysts was significantly less and greater, respectively (p< 0.05), than in controls.

conclusionOur results showed, that the alteration ofH3K4me3 and H3K9me3 methylation, change

Indexed as

Chimeric blastocystsH19/Igf2Histone 3 (H3) methylation

Identifiers

PMID33649730
PMCPMC7816783
OpenAlexW3115291939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.