Evidence map›Paper›PMID 33649600›Full record

ArticleNature chemical biology2021

Reply to: Binding site for MDL-801 on SIRT6.

Zhimin Huang, Junxing Zhao, Wei Deng, Yingyi Chen, Jialin Shang, Kun Song, Lu Zhang, Chengxiang Wang, Shaoyong Lu, Xiuyan Yang and 17 more

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in Nature chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Cryo-EM structure of the human Sirtuin 6-nucleosome complex.bioRxiv : the preprint server for biology · 2023
    Article
  5. Review
  6. Emerging Therapeutic Potential of SIRT6 Modulators.Journal of medicinal chemistry · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Zhimin HuangDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0001-9230-6039
Junxing ZhaoDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Wei DengDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yingyi ChenDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Jialin ShangDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Kun SongDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Lu ZhangDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Chengxiang WangDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Shaoyong LuDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xiuyan YangDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Bin HeEngineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guizhou Medical University, Guiyang, China.
Jinrong MinStructural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.
Hao HuShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0003-1365-0267
Minjia TanShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0002-6784-9653
Jianrong XuDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Qiufen ZhangDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Jie ZhongDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xiaoxiang SunSchool of Life Sciences and Technology, Tongji University, Shanghai, China.
Zhiyong MaoSchool of Life Sciences and Technology, Tongji University, Shanghai, China.ORCID http://orcid.org/0000-0002-5298-1918
Houwen LinDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Mingzhe XiaoShanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Y Eugene ChinShanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Hualiang JiangShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Honghua ShenAilewei Company, Shanghai, China.
Ying XuDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Guoqiang ChenDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-4936-2363
Jian ZhangDepartment of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, China. jian.zhang@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-6558-791X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

SirtuinsBinding SitesProtein DomainsSirtuins

Identifiers

PMID33649600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.