ArticleJournal of perinatology : official journal of the California Perinatal Association2021
Fetal cardiac dimensions in congenital diaphragmatic hernia: relationship with gestational age and postnatal outcomes.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Hemodynamic Phenotypes in Congenital Diaphragmatic Hernia: Unresolved Questions and Future Directions.Children (Basel, Switzerland) · 2026Article
- Cardiorespiratory transition in CDH.Seminars in fetal & neonatal medicine · 2025Review
- Congenital Diaphragmatic Hernia Patients with Left Heart Hypoplasia and Left Ventricular Dysfunction Have Highest Odds of Mortality.The Journal of pediatrics · 2024Article
- Epidemiology of congenital diaphragmatic hernia among 24 million Chinese births: a hospital-based surveillance study.World journal of pediatrics : WJP · 2024Article
- The brain of fetuses with congenital diaphragmatic hernia shows signs of hypoxic injury with loss of progenitor cells, neurons, and oligodendrocytes.Scientific reports · 2024Article
- Fetal MRI-Based Mediastinal Shift Angle (MSA) and Percentage Area of Left Ventricle (pALV) as Prognostic Parameters for Congenital Diaphragmatic Hernia.Journal of clinical medicine · 2024Article
- Prenatal diagnosis and risk stratification of congenital diaphragmatic hernia.World journal of pediatric surgery · 2024Review
- Right to left ventricular volume ratio is associated with mortality in congenital diaphragmatic hernia.Pediatric research · 2023Article
- Early nitric oxide is not associated with improved outcomes in congenital diaphragmatic hernia.Pediatric research · 2023Article
- Inotropic score and vasoactive inotropic score as predictors of outcomes in congenital diaphragmatic hernia: A single center retrospective study.Frontiers in pediatrics · 2023Article
- Congenital diaphragmatic hernia.Nature reviews. Disease primers · 2022Review
- The heart in congenital diaphragmatic hernia: Knowns, unknowns, and future priorities.Frontiers in pediatrics · 2022Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo serially assess fetal cardiac dimensions in congenital diaphragmatic hernia (CDH) and their relation to disease severity. STUDY
designRetrospective analysis of CDH cases and matched controls. Mitral (MVd) and tricuspid (TVd) valve diameters, left (LV) and right (RV) ventricular length and area, Z-scores, were serially assessed at 24-26, 30-32, and 35-37 weeks gestational age (GA).
resultsIn CDH cases MVd, MVd Z-score, and LV area were significantly reduced at 24-26 and 35-37 weeks GA. TVd, TVd Z-score, and RV area were significantly reduced at 24-26 weeks. RV area Z-score increased with advancing GA. MVd and MVd Z-score were significantly lower at 24-26 weeks GA in CDH who had a combined outcome of death and/or ECMO.
conclusionsLV hypoplasia in CDH is characterized by reduced MVd from 24 weeks GA. MVd, and the ratio of mitral and tricuspid valve diameters at later gestations, may be potential predictors of disease severity.
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Registered trials
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