Evidence map›Paper›PMID 33649304›Full record

ReviewNature communications2021

DNA stability: a central design consideration for DNA data storage systems.

Karishma Matange, James M Tuck, Albert J Keung

Abstract readReview
In one paragraph

Review in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

  1. Article
  2. Article
  3. Ribonucleotide errors, RNase HII, and ribonucleotide excision repair.Critical reviews in biochemistry and molecular biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Primer-Disk-Enabled DNA Data Storage System with Index and Record-Many-Read-Many Features.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karishma MatangeDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0002-3257-9083
James M TuckDepartment of Electrical and Computer Engineering, North Carolina State University, Raleigh, NC, USA. jtuck@ncsu.edu.ORCID 0000-0001-8975-0294
Albert J KeungDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, USA. ajkeung@ncsu.edu.ORCID 0000-0001-8958-1232

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data storage in DNA is a rapidly evolving technology that could be a transformative solution for the rising energy, materials, and space needs of modern information storage. Given that the information medium is DNA itself, its stability under different storage and processing conditions will fundamentally impact and constrain design considerations and data system capabilities. Here we analyze the storage conditions, molecular mechanisms, and stabilization strategies influencing DNA stability and pose specific design configurations and scenarios for future systems that best leverage the considerable advantages of DNA storage.

Indexed as

Data SystemsInformation Storage and RetrievalDNADNA

Identifiers

PMID33649304
PMCPMC7921107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.