ArticleAnnals of hepato-biliary-pancreatic surgery2021
Clinicopathological features and post-resection outcomes of hepatocellular adenoma.
Article in Annals of hepato-biliary-pancreatic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Role of ADC in differentiating hepatocellular adenoma vs. hepatocellular carcinoma and metastatic liver lesions: systematic review and meta-analysis.Abdominal radiology (New York) · 2026Pooled it
- Surgical Selection of T1 Stage Renal Tumor Resection Based on Imaging MAP Score under Smart Medical Care.Computational intelligence and neuroscience · 2022Article
- Surgical Strategy and Prognosis of Pancreatic Neuroendocrine Tumors Based on Smart Medical Imaging.Contrast media & molecular imaging · 2022Article
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Authors and funding
10 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUNDS/
aimsHepatocellular adenomas (HCA) are rare benign liver tumors with the potential of malignant transformation and risk of bleeding. We investigated the clinicopathological features and outcomes of HCA in 19 patients who underwent surgical resection.
methodsThis retrospective observational study included 19 patients who underwent hepatic resection during a 9-year period from 2011 to 2019.
resultsThe incidence of HCA was 0.18% of all hepatic resection cases during the study period. The mean age of the patients was 34.3±9.6 years, and 12 patients (63.2%) were female. Abdominal pain was present as initial clinical manifestation in 5 patients and the other 14 patients had no specific symptoms. HCA was diagnosed in 7 out of 8 patients who underwent liver biopsy. R0 resection was performed in 18 patients (94.7%) and laparoscopic liver resection was performed in 11 patients (57.9%). The mean tumor size was 5.6±3.6 cm and 17 patients had a single tumor. Immunohistochemical analysis of the resected tumor specimens revealed hepatocyte-nuclear-factor-1
conclusionsSurgical resection may be indicated if imaging studies show diagnostic ambiguity, growing tumor or symptomatic mass. Because of the risk of tumor recurrence and malignant transformation, long-term follow-up is necessary.
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