ArticleProceedings of the National Academy of Sciences of the United States of America2021
Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia.
Open access · greenAbstract readComparative Study
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 23 citations in OpenAlex.
- Epigenetic regulation of neutrophil dysfunction in sepsis: mechanisms, biomarkers, and translational challenges.Journal of translational medicine · 2026Review
- Editorial for the Special Issue "Staphylococcal Biology and Pathogenesis".Antibiotics (Basel, Switzerland) · 2026Article
- Virulence Phenotypes Differentiate Persistent vs. Resolving Isolates of HumanAntibiotics (Basel, Switzerland) · 2026Article
- Methicillin-resistant and susceptible Staphylococcus aureus: tolerance, immune evasion and treatment.Nature reviews. Microbiology · 2026Review
- Early-stage lung adenocarcinoma affects DNA methylation and gene expression in adjacent tissues.EMBO reports · 2025Article
- The lack of a biorepository during vaccine trials: A lost opportunity to understand staphylococcal immunity.Vaccine · 2025Article
- Early cytokine signatures and clinical phenotypes discriminate persistent from resolving MRSA bacteremia.BMC infectious diseases · 2025Article
- Epigenetic mechanisms mediate cytochrome P450 1A1 expression and lung endothelial injury caused by MRSA in vitro and in vivo.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Identification of DNA methylation markers for age and Bovine Respiratory Disease in dairy cattle: A pilot study based on Reduced Representation Bisulfite Sequencing.Communications biology · 2024Article
- The Purine Biosynthesis Repressor, PurR, Contributes to Vancomycin Susceptibility of Methicillin-resistant Staphylococcus aureus in Experimental Endocarditis.The Journal of infectious diseases · 2024Article
- Tensor modeling of MRSA bacteremia cytokine and transcriptional patterns reveals coordinated, outcome-associated immunological programs.PNAS nexus · 2024Article
- Longitudinal analysis of influenza vaccination implicates regulation of RIG-I signaling by DNA methylation.Scientific reports · 2024Article
- Integrated transcriptomic analysis reveals immune signatures distinguishing persistent versus resolving outcomes in MRSA bacteremia.Frontiers in immunology · 2024Article
- Staphylococcus aureus host interactions and adaptation.Nature reviews. Microbiology · 2023Review
- Quantifying stimulus-response specificity to probe the functional state of macrophages.Cell systems · 2023Article
- Persistent Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023Review
- MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony VariantsInfection and immunity · 2023Article
- DNA methylation profiles in pneumonia patients reflect changes in cell types and pneumonia severity.Epigenetics · 2022Article
- Review
- The Role of Host Cell DNA Methylation in the Immune Response to Bacterial Infection.Frontiers in immunology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 1 country.
Yu-Ling ChangDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.ORCID 0000-0002-0789-4989
Maura RossettiDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
David W GjertsonDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
Liudmilla RubbiDepartment of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA 90095.
Michael ThompsonDepartment of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA 90095.ORCID 0000-0002-2914-1080
Dennis J MontoyaSchool of Medicine, University of California, Davis, CA 95616.ORCID 0000-0002-0802-3309
Marco MorselliDepartment of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA 90095.ORCID 0000-0003-3351-5791
Felicia RuffinDivision of Infectious Diseases, Duke University, Durham, NC 27710.
Alexander HoffmannInstitute for Quantitative and Computational Biosciences, University of California, Los Angeles, CA 90095.ORCID 0000-0002-5607-3845
Matteo PellegriniDepartment of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA 90095.ORCID 0000-0001-9355-9564
Vance G FowlerDivision of Infectious Diseases, Duke University, Durham, NC 27710.ORCID 0000-0002-8048-0897
Michael R YeamanDivision of Molecular Medicine, Harbor-University of California, Los Angeles Medical Center, Torrance, CA 90502.
Elaine F ReedDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095; EReed@mednet.ucla.edu.
with the MRSA Systems Immunology Group
University of California, Los Angeles · USDuke University · USQB3 · USUniversity of California, Davis · US
Funding
The Effect of Nanoparticle Encapsulated Resveratrol on Treatment of PeriodontitisKL2TR001882 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Elizabeta Nemeth · 2016 to 2026
$13.1MProject 3: Mapping the Evolution of Chronic Transplant Injury in the Context of CMV InfectionU19AI128913 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI REED, ELAINE F, SARWAL, MINNIE M · 2017 to 2021
$11.2MSystems Immunolobiology of Antibiotic-Persistent MRSA InfectionU01AI124319 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI YEAMAN, MICHAEL R · 2016 to 2020
$10.1MHost Susceptibility to S. aureusR01AI068804 · NIAID · DUKE UNIVERSITY · PI FOWLER, VANCE G. · 2007 to 2016
$6.9MThe role of purine biosynthesis and stringent response in persistent MRSA endovascular infectionsR01AI139244 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI XIONG, YAN Q. · 2019 to 2023
$2.2MMitigating Resistance & Virulence in MRSAR33AI111661 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI YEAMAN, MICHAEL R · 2016 to 2018
$1.2MNCATS NIH HHS KL2 TR001882NIAID NIH HHS R01 AI068804NIAID NIH HHS R01 AI139244NIAID NIH HHS R33 AI111661NIAID NIH HHS U01 AI124319NIAID NIH HHS U19 AI128913
Abstract
Persistent methicillin-resistant
Indexed as
DNA MethylationResponse ElementsAnti-Bacterial AgentsBacteremiaCCAAT-Enhancer-Binding Protein-betaFemaleHumansMaleMethicillin-Resistant Staphylococcus aureusMiddle Agedp300-CBP-Associated Factorp300-CBP Transcription FactorsStaphylococcal InfectionsSTAT1 Transcription FactorAnti-Bacterial AgentsCCAAT-Enhancer-Binding Protein-betaCEBPB protein, humanp300-CBP-Associated Factorp300-CBP Transcription FactorsSTAT1 protein, humanSTAT1 Transcription FactorDNA methylationepigeneticsMRSApersistenceStaphylococcus aureus
Identifiers
What OpenQuestion holds
Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.