Evidence map›Paper›PMID 33649149›Full record

ReviewJournal of bacteriology2021

G-Quadruplex Structures in Bacteria: Biological Relevance and Potential as an Antimicrobial Target.

Puja Yadav, Nayun Kim, Monika Kumari, Shalini Verma, Tarun Kumar Sharma, Vikas Yadav, Amit Kumar

Open access · greenAbstract readReview
In one paragraph

Review in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
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  14. eLife · 2024
    Article
  15. Kinetic Features of Degradation of R-Loops by RNase H1 fromInternational journal of molecular sciences · 2024
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Puja YadavDepartment of Microbiology, Central University of Haryana, Mahendergarh, Haryana, India.
Nayun KimDepartment of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, The University of Texas Graduate School of Biomedical Sciences, Houston, Texas, USA.
Monika KumariDepartment of Microbiology, Central University of Haryana, Mahendergarh, Haryana, India.
Shalini VermaDepartment of Microbiology, Central University of Haryana, Mahendergarh, Haryana, India.
Tarun Kumar SharmaTranslational Health Science and Technology Institute, Faridabad, Haryana, India.
Vikas YadavSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Amit KumarDiscipline of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Simrol, Indore, India.
Central University of Haryana · INIndian Institute of Technology Indore · INJawaharlal Nehru University · INThe University of Texas Health Science Center at Houston · USTranslational Health Science and Technology Institute · IN

Funding

G-Quadruplex forming sequence motifs and genome instabilityR01GM116007 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KIM, NAYUN · 2016 to 2020
$1.7M
NIGMS NIH HHS R01 GM116007
6 · The paper itself

Abstract

DNA strands consisting of multiple runs of guanines can adopt a noncanonical, four-stranded DNA secondary structure known as G-quadruplex or G4 DNA. G4 DNA is thought to play an important role in transcriptional and translational regulation of genes, DNA replication, genome stability, and oncogene expression in eukaryotic genomes. In other organisms, including several bacterial pathogens and some plant species, the biological roles of G4 DNA and G4 RNA are starting to be explored. Recent investigations showed that G4 DNA and G4 RNA are generally conserved across plant species.

Indexed as

G-QuadruplexesAnimalsAnti-Infective AgentsBacteriaDNA, BacterialGene Expression Regulation, BacterialGenome, BacterialGenomic InstabilityGuanineHumansLigandsVirulenceAnti-Infective AgentsDNA, BacterialGuanineLigandsantigenic variationaptamersG-quadruplexhomologous recombinationhost-pathogen interactiontranscriptional and translational regulation

Identifiers

PMID33649149
PMCPMC8315935
OpenAlexW3133967603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.