Evidence map›Paper›PMID 33649104›Full record

ArticleMolecular cancer therapeutics2021

Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis.

Yuhua Wang, Ram Naresh Pandey, Kaushik Roychoudhury, David Milewski, Tanya V Kalin, Sara Szabo, Joseph G Pressey, Rashmi S Hegde

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. All eyes on Eya: A unique transcriptional co-activator and phosphatase in cancer.Biochimica et biophysica acta. Reviews on cancer · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Molecularly Defined Subsets of Ewing Sarcoma Tumors Differ in Their Responses to IGF1R and WEE1 Inhibition.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  10. Inhibitors of EYA3 Protein in Ewing Sarcoma.Asian Pacific journal of cancer prevention : APJCP · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuhua Wang *Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Ram Naresh Pandey *Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Kaushik RoychoudhuryDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.ORCID 0000-0002-9585-7722
David MilewskiDivision of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.ORCID 0000-0002-9778-8548
Tanya V KalinDivision of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Sara SzaboDivision of Pathology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.ORCID 0000-0002-6212-7264
Joseph G PresseyCancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.ORCID 0000-0003-1816-3281
Rashmi S HegdeDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio. rashmi.hegde@cchmc.org.
Cincinnati Children's Hospital Medical Center · US

Funding

Development of novel therapeutic approaches for treatment of Alveolar Capillary DysplasiaR01HL152973 · NHLBI · UNIVERSITY OF ARIZONA · PI Vladimir Kalinichenko · 2021 to 2026
$3.6M
A ROLE FOR EYA3 IN VASCULAR REMODELING AND PULMONARY ARTERIAL HYPERTENSIONR01HL152094 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI HEGDE, RASHMI S. · 2020 to 2023
$2.3M
Role of lung endothelial cells during fibrotic lung remodeling.R01HL158659 · NHLBI · UNIVERSITY OF ARIZONA · PI KALIN, TANYA · 2021 to 2024
$2.2M
Linked regulation of tumor angiogenesis and chemo-resistanceR01CA207068 · NCI · CINCINNATI CHILDRENS HOSP MED CTR · PI HEGDE, RASHMI S. · 2017 to 2021
$1.8M
NCI NIH HHS R01 CA207068NHLBI NIH HHS R01 HL152094NHLBI NIH HHS R01 HL152973NHLBI NIH HHS R01 HL158659
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorDNA-Binding ProteinsDNA DamageFemaleHumansMiceNeovascularization, PathologicSarcoma, EwingDNA-Binding ProteinsEya3 protein, mouse

Identifiers

PMID33649104
PMCPMC8102334
OpenAlexW3134342895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.