Evidence map›Paper›PMID 33648423›Full record

ArticleAdipocyte2021

Effects of non-vascularized adipose tissue transplantation on its genetic profile.

Jeannine S Schreiter, L O Kurow, S Langer, M Steinert, L Massier

Open access · goldAbstract read
In one paragraph

Article in Adipocyte, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jeannine S SchreiterKlinik am Rosental GmbH Leipzig, Leipzig, Germany.
L O KurowDepartment of Orthopedics, Traumatology and Plastic Surgery.
S LangerDepartment of Orthopedics, Traumatology and Plastic Surgery.
M SteinertDepartment of Thoracic Surgery, University Hospital Leipzig, Leipzig, Germany.
L MassierUniversity Hospital Leipzig, Leipzig, Germany.
University Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subcutaneous adipose tissue (SAT) is recognized as a highly active metabolic and inflammatory tissue. Interestingly, adipose tissue transplantation is widely performed in plastic surgery via lipofilling, yet little is known about the gene alteration of adipocytes after transplantation. We performed an RNA-expression analysis of fat transplants before and after fat transplantation.In C57BL/6 N mice SAT was autologously transplanted. Samples of SAT were analysed before transplantation, 7, and 15 days after transplantation and gene expression profiles were measured.Analysis revealed that lipid metabolism-related genes were downregulated while inflammatory and extracellular matrix related genes were up-regulated 7 and 15 days after transplantation. When comparing gene expression profile 7 days after transplantation to 15 days after transplantation developmental pathways showed most changes.

Indexed as

AdipocytesAdipose TissueAnimalsExtracellular MatrixFemaleGene ExpressionGene Expression ProfilingInflammationLipid MetabolismMiceMice, Inbred C57BLSubcutaneous FatTranscriptomeTransplantsAdipose tissuefat transplantationgene expressiongene ontologyinsulin resistance

Identifiers

PMID33648423
PMCPMC7928050
OpenAlexW3134568999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.