Evidence map›Paper›PMID 33648390›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2021

Activation of carbonic anhydrase isoforms involved in modulation of emotional memory and cognitive disorders with histamine agonists, antagonists and derivatives.

Gustavo Provensi, Alessio Nocentini, Maria Beatrice Passani, Patrizio Blandina, Claudiu T Supuran

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. New isoxazolidinyl-basedJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Activation studies with amino acids and amines of a β-carbonic anhydrase fromJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Carbonic anhydrase activation profile of indole-based derivatives.Journal of enzyme inhibition and medicinal chemistry · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gustavo ProvensiDepartment of NEUROFARBA, University of Florence, Section of Pharmacology and Toxicology, Firenze, Italy.ORCID https://orcid.org/0000-0002-6182-6848
Alessio NocentiniDepartment of NEUROFARBA, University of Florence, Section of Pharmacology and Toxicology, Firenze, Italy.ORCID https://orcid.org/0000-0003-3342-702X
Maria Beatrice PassaniDepartment of Health Science, University of Florence, Section of Clinical Pharmacology and Oncology, Firenze, Italy.
Patrizio BlandinaDepartment of NEUROFARBA, University of Florence, Section of Pharmacology and Toxicology, Firenze, Italy.
Claudiu T SupuranDepartment of NEUROFARBA, University of Florence, Section of Pharmacology and Toxicology, Firenze, Italy.ORCID https://orcid.org/0000-0003-4262-0323
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbonic anhydrases (CAs, EC 4.2.1.1) activators were shown to be involved in memory enhancement and learning in animal models of cognition. Here we investigated the CA activating effects of a large series of histamine based compounds, including histamine receptors (H

Indexed as

Carbonic AnhydrasesCognition DisordersEmotionsHistamine AgonistsHistamine AntagonistsHumansIsoenzymesMemoryMolecular StructureCarbonic AnhydrasesHistamine AgonistsHistamine AntagonistsIsoenzymesactivatorsagonists/antagonistsCarbonic anhydrasecognition-related disordershistamine receptors

Identifiers

PMID33648390
PMCPMC7928026
OpenAlexW3135039456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.