Evidence map›Paper›PMID 33647588›Full record

Trial reportDrug and alcohol dependence2021

How adolescents' working memory abilities relate to their alcohol craving in real-life contexts depends on biological sex.

Hayley Treloar Padovano, Robert Miranda

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Hayley Treloar PadovanoDepartment of Psychiatry and Human Behavior, Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University, Box G-S121-4, Providence, RI, 02912, United States. Electronic address: hayley_treloar@brown.edu.
Robert MirandaDepartment of Psychiatry and Human Behavior, Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University, Box G-S121-4, Providence, RI, 02912, United States. Electronic address: robert_miranda_jr@brown.edu.
Brown University · USJohn Brown University · US

Funding

NALTREXONE, CRAVING AND DRINKING: ECOLOGICAL ASSESSMENTR01AA007850 · NIAAA · BROWN UNIVERSITY · PI MIRANDA, ROBERT · 1988 to 2015
$8.4M
Mentored Patient-Oriented Research on Adolescent Alcohol Misuse and TreatmentK24AA026326 · NIAAA · BROWN UNIVERSITY · PI ROBERT MIRANDA · 2018 to 2026
$1.7M
Novel Approaches to Understanding How Alcohol Pathology Develops in AdolescentsK23AA024808 · NIAAA · BROWN UNIVERSITY · PI TRELOAR PADOVANO, HAYLEY · 2017 to 2021
$973k
NIAAA NIH HHS K23 AA024808NIAAA NIH HHS K24 AA026326NIAAA NIH HHS R01 AA007850
6 · The paper itself

Abstract

aimWe sought to elucidate whether stress, peers, and in vivo (i.e., direct) alcohol cues elicit alcohol craving in daily life among adolescents and to test whether individual variation in working memory function and biological sex alters these associations.

methodsWe leveraged ecological momentary assessment (EMA) to examine momentary associations between stress, peers, and direct alcohol cues with craving, assessed as "urge to drink alcohol," among 86 male (51.2 %) and female (48.8 %) frequent drinkers (i.e., two or more drinking days per week). Participants were ages 14-24 years (M = 20.7 years, SD = 2.1). Participants completed EMA throughout the day for about one week prior to randomization to a treatment condition for an AUD clinical trial. Pre-registered, secondary analyses focused on craving for assessments when adolescents were not drinking, and assessments occurring after drinking on drinking days were removed. Working memory performance was assessed in the laboratory via the Memory for Words subtest of the Woodcock-Johnson III Tests of Cognitive Abilities.

resultsCraving was heightened at more stressful moments and when adolescents were with their peers and in the presence of direct alcohol cues. Working memory function was not related to craving but altered the relation of momentary stress, peers, and cues with craving once biological sex-related differences were considered. Females generally had lower craving than males, but working memory function served to buffer against stress-induced craving for males.

conclusionsHigher working memory function buffered the in-the-moment relation of stress with alcohol craving for males but not females.

Indexed as

Ecological Momentary AssessmentSex CharacteristicsAdolescentAlcoholismCravingFemaleHumansMaleMemory, Short-TermPeer GroupSurveys and QuestionnairesUnderage DrinkingYoung AdultAdolescentsAlcoholCravingEcological momentary assessmentStress

Identifiers

PMID33647588
PMCPMC8026543
OpenAlexW3131663868

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.