Evidence map›Paper›PMID 33647202›Full record

ArticleAnalytical chemistry2021

Microfluidics-Coupled Radioluminescence Microscopy for

Tae Jin Kim, Byunghang Ha, Alison Dana Bick, Minkyu Kim, Sindy K Y Tang, Guillem Pratx

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Development of a Lensless Radiomicroscope for Cellular-Resolution Radionuclide Imaging.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tae Jin KimDivision of Medical Physics, Department of Radiation Oncology, Stanford University, 300 Pasteur Dr., Stanford, California 94305, United States.ORCID 0000-0002-1732-7398
Byunghang HaDepartment of Mechanical Engineering, Stanford University, 440 Escondido Mall, Stanford, California 94305, United States.
Alison Dana BickDepartment of Mechanical Engineering, Stanford University, 440 Escondido Mall, Stanford, California 94305, United States.
Minkyu KimDepartment of Mechanical Engineering, Stanford University, 440 Escondido Mall, Stanford, California 94305, United States.
Sindy K Y TangDepartment of Mechanical Engineering, Stanford University, 440 Escondido Mall, Stanford, California 94305, United States.ORCID 0000-0003-1465-2432
Guillem PratxDivision of Medical Physics, Department of Radiation Oncology, Stanford University, 300 Pasteur Dr., Stanford, California 94305, United States.ORCID 0000-0002-0247-6470
Stanford University · US

Funding

Stanford Molecular Imaging Scholars (SMIS) ProgramT32CA118681 · NCI · STANFORD UNIVERSITY · PI CRAIG S LEVIN · 2016 to 2026
$4.3M
High-throughput radionuclide counting and sorting of single cellsR21CA193001 · NCI · STANFORD UNIVERSITY · PI PRATX, GUILLEM · 2015 to 2017
$698k
NCI NIH HHS R21 CA193001NCI NIH HHS T32 CA118681
6 · The paper itself

Abstract

Integrated bioassay systems that combine microfluidics and radiation detectors can deliver medical radiopharmaceuticals to live cells with precise timing, while minimizing radiation dose and sample volume. However, the spatial resolution of many radiation imaging systems is limited to bulk cell populations. Here, we demonstrate microfluidics-coupled radioluminescence microscopy (μF-RLM), a new integrated system that can image radiotracer uptake in live adherent cells growing inside microincubators with spatial resolution better than 30 μm. Our method enables on-chip radionuclide imaging by incorporating an inorganic scintillator plate (CdWO

Indexed as

MicrofluidicsMicroscopyFluorodeoxyglucose F18KineticsPositron-Emission TomographyRadiopharmaceuticalsFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID33647202
PMCPMC8006742
OpenAlexW3134848088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.