Evidence map›Paper›PMID 33647023›Full record

ArticlePloS one2021

Phasic heart rate variability and the association with cognitive performance: A cross-sectional study in a healthy population setting.

Kathrin Hilgarter, Karin Schmid-Zalaudek, Regina Csanády-Leitner, Manfred Mörtl, Andreas Rössler, Helmut Karl Lackner

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  6. Prediction model for mild cognitive impairment in patients with type 2 diabetes using the autonomic function test.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kathrin HilgarterDivision of Physiology, Otto Loewi Research Centre, Medical University of Graz, Graz, Austria.ORCID 0000-0001-9051-3296
Karin Schmid-ZalaudekDivision of Physiology, Otto Loewi Research Centre, Medical University of Graz, Graz, Austria.
Regina Csanády-LeitnerDivision of Physiology, Otto Loewi Research Centre, Medical University of Graz, Graz, Austria.
Manfred MörtlDepartment of Obstetrics and Gynecology, Clinical Centre Klagenfurt, Klagenfurt, Austria.
Andreas RösslerDivision of Physiology, Otto Loewi Research Centre, Medical University of Graz, Graz, Austria.
Helmut Karl LacknerDivision of Physiology, Otto Loewi Research Centre, Medical University of Graz, Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSympathovagal balance measured by heart rate variability is a core component of psychophysiological research. Through the close link of physiological and psychological aspects, often a reduced heart rate variability is associated with impaired cognitive function. A better understanding of the associations between cognitive and cardiovascular dysfunctions is necessary to prevent the manifestation of diseases. Therefore, this study investigated phasic heart rate variability using rest, anticipatory, stress, and recovery periods and the association with high and low cognitive performance in a generally healthy population setting.

methods114 healthy individuals (40 males, 74 females) aged 20 to 70 participated in the cross-sectional study. The heart rate variability based on standard deviation of NN intervals (SDNN), and the root means square of successive differences (RMSSD), low frequency (LF), high frequency (HF) and LF/HF ratio and its association with high and low cognitive performance measured by the California Verbal Learning Task II were examined.

resultsThe results of this study indicate that the paradigm was successful in producing stress and showed a significant association between phasic heart rate variability (SDNN) and verbal episodic memory performance, irrespective of age and sex. DISCUSSION: The results of this study suggest that a reduced heart rate variability is associated with reduced cognitive function regardless of age and sex and seem to be an early indicator of sympathovagal disbalance.

conclusionThis leads to the conclusion that differences between high and low cognitive performance might show differences in heart rate variability at an early stage, where no diseases are yet manifest.

Indexed as

Healthy VolunteersHeart RateAdultCognitionCross-Sectional StudiesFemaleHumansMaleMiddle AgedYoung Adult

Identifiers

PMID33647023
PMCPMC7920382

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.