Evidence map›Paper›PMID 33646426›Full record

ArticleAmino acids2021

New approaches towards the synthesis of 1,2,3,4-tetrahydro isoquinoline-3-phosphonic acid (Tic

José Luis Viveros-Ceballos, Lizeth A Matías-Valdez, Francisco J Sayago, Carlos Cativiela, Mario Ordóñez

Abstract read
PubMed Publisher
In one paragraph

Article in Amino acids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Synthesis of Amino-Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

José Luis Viveros-CeballosCentro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, 62209, Cuernavaca, Morelos, Mexico. jlvc@uaem.mx.ORCID http://orcid.org/0000-0003-0202-4180
Lizeth A Matías-ValdezCentro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, 62209, Cuernavaca, Morelos, Mexico.
Francisco J SayagoDepartamento de Química Orgánica, ISQCH, Universidad de Zaragoza, CSIC, 50009, Zaragoza, Spain.ORCID http://orcid.org/0000-0001-5652-5170
Carlos CativielaDepartamento de Química Orgánica, ISQCH, Universidad de Zaragoza, CSIC, 50009, Zaragoza, Spain.ORCID http://orcid.org/0000-0003-3222-0828
Mario OrdóñezCentro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, 62209, Cuernavaca, Morelos, Mexico. palacios@uaem.mx.ORCID http://orcid.org/0000-0001-9395-7079

Funding

Consejo Nacional de Ciencia y Tecnología (CONACYT) 256985Consejo Nacional de Ciencia y Tecnología (CONACYT) 286614Gobierno de Aragon-FEDER FEDER 2014-2020
6 · The paper itself

Abstract

Two new strategies for the efficient synthesis of racemic 1,2,3,4-tetrahydroisoquinoline-3-phosphonic acid (Tic

Indexed as

CyclizationDecarboxylationMolecular StructurePeptidomimeticsPhosphorous AcidsPhosphorylationStereoisomerismTetrahydroisoquinolines1,2,3,4-tetrahydroisoquinolinePeptidomimeticsphosphonic acidPhosphorous AcidsTetrahydroisoquinolinesN-Acyliminium ionPhosphorylationRadical fragmentationWittig–Horner and Pictet–Spengler reactionsα-Aminophosphonic acidsα,β-Dehydroaminophosphonate

Identifiers

PMID33646426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.