Evidence map›Paper›PMID 33646315›Full record

ArticleJAMA network open2021

Racial Disparities in Diagnosis of Attention-Deficit/Hyperactivity Disorder in a US National Birth Cohort.

Yu Shi, Lindsay R Hunter Guevara, Hayley J Dykhoff, Lindsey R Sangaralingham, Sean Phelan, Michael J Zaccariello, David O Warner

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05796427 (Testing a Novel ADHD Engagement Intervention "START" to Improve Access to Treatment), which is not on this map. Cited by 73 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 4 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05796427 nacompletednot on this mapstarted 2023, after this paper: background citation

Testing a Novel ADHD Engagement Intervention "START" to Improve Access to Treatment

TypeinterventionalSponsorAnn & Robert H Lurie Children's Hospital of ChicagoRan2023 to 2025Enrolled100ConditionsADHDArmsSupporT for ADHD and Related Treatment
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 4 syntheses or guidelines pooled it, 142 citations in OpenAlex.

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  17. Prior Diagnoses and Age of Diagnosis in Children Later Diagnosed with Autism.Journal of autism and developmental disorders · 2026
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yu ShiDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Lindsay R Hunter GuevaraDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Hayley J DykhoffDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Lindsey R SangaralinghamDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Sean PhelanDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Michael J ZaccarielloDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.
David O WarnerDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · USMayo Clinic in Florida · USOptum (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: There are limited data on the racial disparities in the incidence of attention-deficit/hyperactivity disorder (ADHD) diagnosis in children at the national level. Objective: To explore differences in rates of diagnosis of ADHD and use of treatment among children by race and ethnicity. Design, Setting, and Participants: This retrospective cohort study assessed insurance claims data of children born in the US between January 1, 2006, and December 31, 2012, who had continuous insurance coverage for at least 4 years. The last date of follow-up included in the cohort was June 30, 2019. Race/ethnicity designations were based on self-report and included non-Hispanic White, Black, Hispanic, and Asian. Data were analyzed between October 2019 and December 2020. Exposures: Race and ethnicity. Main Outcomes and Measures: ADHD diagnosis as defined by International Classification of Diseases codes (ninth or tenth editions) and treatment within 1 year of diagnosis, including medication and behavior therapy as defined by billing codes. Data on ADHD diagnosis and treatment were adjusted for sex, region, and household income in a multivariate Cox regression model. Results: Among 238 011 children in the cohort (116 093 [48.8%] girls; 15 183 [6.7%] Asian, 14 792 [6.2%] Black, 23 358 [9.8%] Hispanic, and 173 082 [72.7%] White children), 11 401 (4.8%) were diagnosed with ADHD. The cumulative incidence at age 12 was 13.12% (95% CI, 12.79%-13.46%). In multivariate Cox regression adjusting for sex, region, and household income, the hazard ratio for Asian children was 0.48 (95% CI, 0.43-0.53); Black children, 0.83 (95% CI, 0.77-0.90); and Hispanic children, 0.77 (95% CI, 0.72, 0.82) compared with White children. In the first year after diagnosis, 516 preschool children (19.4%) received behavioral therapy only, 860 (32.4%) had medications only, 505 (19.0%) had both, and 774 (29.2%) had no claims associated with either option. A higher percentage of school-aged children (2904 [65.6%]) were prescribed medications, and fewer had therapy only (639 [14.4%]) or no treatment at all (884 [20.0%]). Compared with other groups, White children were more likely to receive some kind of treatment. Asian children had the highest odds of receiving no treatment (odds ratio compared with White children, 0.54; 95% CI, 0.42-0.70). Conclusions and Relevance: Racial and ethnic disparities in the diagnosis and treatment of ADHD are evident. Future study is needed to elucidate the mechanism behind these disparities, with special attention to Asian children. Clinicians should provide racially sensitive care in the evaluation and treatment of ADHD.

Indexed as

AsianAttention Deficit Disorder with HyperactivityBlack or African AmericanChildChild, PreschoolCohort StudiesFemaleHealthcare DisparitiesHispanic or LatinoHumansMaleRetrospective StudiesUnited StatesWhite People

Identifiers

PMID33646315
PMCPMC7921900
OpenAlexW3135641158

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.