ArticleJournal of Alzheimer's disease : JAD2021
Race/Ethnic Disparities in Mild Cognitive Impairment and Dementia: The Northern Manhattan Study.
Article in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.
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Who cites it
61 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Overlooked cases of mild cognitive impairment: Implications to early Alzheimer's disease.Ageing research reviews · 2024Pooled it
- Prediction model for cognitive frailty in older adults: A systematic review and critical appraisal.Frontiers in aging neuroscience · 2023Pooled it
- Chemokine CXCL10 and Incident Stroke Risk in the Northern Manhattan Study.Translational stroke research · 2026Article
- Hearing and Cognitive Function in Aged Adults: A Machine Learning and Mediation Analysis of NHANES.World journal of otorhinolaryngology - head and neck surgery · 2026Article
- A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Diagnosis of Alzheimer's disease and related dementias and outmigration of older Puerto Rican Medicare Fee-for-Service beneficiaries, 2012-2019.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Childhood maltreatment and joint trajectories of social isolation and depression as predictors of cognitive impairment in late midlife: a prospective cohort study.Epidemiology and psychiatric sciences · 2026Article
- White matter hyperintensities, cognitive decline and dementia risk in a community- dwelling cohort of northern Manhattan.Research square · 2026Article
- Deep survival modeling to predict future cognitive impairment in unimpaired adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Predictors of cognitive resilience in the old-old: An observational study using real-world electronic health record data.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Observational
- Heterogeneity in healthy aging among U.S. Latinos: a dual functionality perspective.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Clinical validation of MyCog Mobile: development of a parsimonious and clinically interpretable prediction model for mild cognitive impairment.JAMIA open · 2026Article
- Oxylipin composition of high-density lipoprotein is altered in men and Hispanic adults with mild cognitive impairment.Journal of lipid research · 2026Article
- Vascular contribution to cognitive impairment and dementia (VCID): proceedings of 2025 workshop of the Jackson Laboratory.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- Chemokines CXCL9 and CCL2 in Relation to Cerebral White Matter Disease, Cognitive Decline, and Dementia: The Northern Manhattan Study.Neurology open access · 2026Article
- Assessing Functional Cognition in People on Maintenance Hemodialysis Using Performance-Based Testing.Kidney360 · 2026Article
- Impact of long-term systolic blood pressure on cognitive disorder risk: Across different age groups and antihypertensive medication timing.Journal of Alzheimer's disease : JAD · 2026Observational
- The relationship between socioeconomic factors, social participation, behaviours, and healthy ageing: an analysis of longitudinal data.Frontiers in public health · 2026Article
- Sensory impairments and cognitive impairment among Mexican American older adults: nativity differences.Aging & mental health · 2026Article
- Mild Behavioral Impairment is Associated With Incident Cognitive Decline Among Dementia-Free, Racially Diverse Older Adults: Data From the African Americans Fighting Alzheimer's in Midlife (AA-FAIM) Study.The American journal of geriatric psychiatry. Open science, education, and practice · 2025Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors.
Funding
Abstract
backgroundVariability in dementia rates across racial and ethnic groups has been estimated at 60%. Studies suggest disparities in Caribbean Hispanic and Black populations, but community-based data are limited.
objectiveEstimate the prevalence of mild cognitive impairment (MCI) and dementia in the racially and ethnically diverse community-based Northern Manhattan Study cohort and examine sociodemographic, vascular risk factor, and brain imaging correlates.
methodsCases of MCI and dementia were adjudicated by a team of neuropsychologists and neurologists and prevalence was estimated across race/ethnic groups. Ordinal proportional odds models were used to estimate race/ethnic differences in the prevalence of MCI or dementia adjusting for sociodemographic variables (model 1), model 1 plus potentially modifiable vascular risk factors (model 2), and model 1 plus structural imaging markers of brain integrity (model 3).
resultsThere were 989 participants with cognitive outcome determinations (mean age 69±9 years; 68% Hispanic, 16% Black, 14% White; 62% women; mean (±SD) follow-up five (±0.6) years). Hispanic and Black participants had greater likelihood of MCI (20%) and dementia (5%) than White participants accounting for age and education differences. Hispanic participants had greater odds of MCI or dementia than both White and Black participants adjusting for sociodemographic variables, vascular risk factors, and brain imaging factors. White matter hyperintensity burden was significantly associated with greater odds of MCI or dementia (OR = 1.3, 1.1 to 1.6), but there was no significant interaction by race/ethnicity.
conclusionIn this diverse community-based cohort, cross-sectional data revealed significant race/ethnic disparities in the prevalence of MCI and dementia. Longer follow-up and incidence data are needed to further clarify these relationships.
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