Evidence map›Paper›PMID 33646127›Full record

ArticleJMIR medical informatics2021

Machine Learning Approach to Predict the Probability of Recurrence of Renal Cell Carcinoma After Surgery: Prediction Model Development Study.

HyungMin Kim, Sun Jung Lee, So Jin Park, In Young Choi, Sung-Hoo Hong

Open access · goldAbstract read
In one paragraph

Article in JMIR medical informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

HyungMin KimDepartment of Medical Informatics, College of Medicine, The Catholic University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-2824-0535
Sun Jung LeeDepartment of Medical Informatics, College of Medicine, The Catholic University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-1087-2051
So Jin ParkDepartment of Medical Informatics, College of Medicine, The Catholic University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-3449-7532
In Young Choi *Department of Medical Informatics, College of Medicine, The Catholic University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-2860-9411
Sung-Hoo Hong *Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-1952-4010
Catholic University of Korea · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal cell carcinoma (RCC) has a high recurrence rate of 20% to 30% after nephrectomy for clinically localized disease, and more than 40% of patients eventually die of the disease, making regular monitoring and constant management of utmost importance.

objectiveThe objective of this study was to develop an algorithm that predicts the probability of recurrence of RCC within 5 and 10 years of surgery.

methodsData from 6849 Korean patients with RCC were collected from eight tertiary care hospitals listed in the KOrean Renal Cell Carcinoma (KORCC) web-based database. To predict RCC recurrence, analytical data from 2814 patients were extracted from the database. Eight machine learning algorithms were used to predict the probability of RCC recurrence, and the results were compared.

resultsWithin 5 years of surgery, the highest area under the receiver operating characteristic curve (AUROC) was obtained from the naïve Bayes (NB) model, with a value of 0.836. Within 10 years of surgery, the highest AUROC was obtained from the NB model, with a value of 0.784.

conclusionsAn algorithm was developed that predicts the probability of RCC recurrence within 5 and 10 years using the KORCC database, a large-scale RCC cohort in Korea. It is expected that the developed algorithm will help clinicians manage prognosis and establish customized treatment strategies for patients with RCC after surgery.

Indexed as

algorithmcancercarcinomadatabasedevelopmentkidneymachine learningmodelnaïve Bayespredictionprobabilityrecurrencerenal cell carcinomasurgeryweb-based

Identifiers

PMID33646127
PMCPMC7961397
OpenAlexW3127445005

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.