Evidence map›Paper›PMID 33646121›Full record

ArticleeLife2021

Cystic proliferation of germline stem cells is necessary to reproductive success and normal mating behavior in medaka.

Luisa F Arias Padilla, Diana C Castañeda-Cortés, Ivana F Rosa, Omar D Moreno Acosta, Ricardo S Hattori, Rafael H Nóbrega, Juan I Fernandino

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Long Non-Coding RNAInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Luisa F Arias PadillaInstituto Tecnológico de Chascomús, INTECH (CONICET-UNSAM), Chascomús, Argentina.ORCID 0000-0003-4689-2561
Diana C Castañeda-CortésReproductive and Molecular Biology Group, Department of Structural and Functional Biology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, Brazil.
Ivana F RosaReproductive and Molecular Biology Group, Department of Structural and Functional Biology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, Brazil.
Omar D Moreno AcostaSalmonid Experimental Station at Campos do Jordão, UPD-CJ, Sao Paulo Fisheries Institute (APTA/SAA), Campos do Jordao, Brazil.
Ricardo S HattoriReproductive and Molecular Biology Group, Department of Structural and Functional Biology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, Brazil.
Rafael H NóbregaInstituto Tecnológico de Chascomús, INTECH (CONICET-UNSAM), Chascomús, Argentina.
Juan I FernandinoInstituto Tecnológico de Chascomús, INTECH (CONICET-UNSAM), Chascomús, Argentina.ORCID 0000-0003-1754-2802
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of an adequate number of gametes is necessary for normal reproduction, for which the regulation of proliferation from early gonadal development to adulthood is key in both sexes. Cystic proliferation of germline stem cells is an especially important step prior to the beginning of meiosis; however, the molecular regulators of this proliferation remain elusive in vertebrates. Here, we report that

Indexed as

Cell ProliferationAnimalsCell Cycle ProteinsFemaleGerm CellsIn Situ HybridizationIntracellular Signaling Peptides and ProteinsMaleN-myc Downstream-Regulated Gene 1 ProteinOryziasSexual Behavior, AnimalTransforming Growth Factor betaCell Cycle ProteinsIntracellular Signaling Peptides and ProteinsN-myc Downstream-Regulated Gene 1 ProteinTransforming Growth Factor betaCRISPR/Cas9developmental biologygametogenesismating vigormitosisndrg1regenerative medicinereproductionstem cells

Identifiers

PMID33646121
PMCPMC7946426
OpenAlexW3133952279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.