Evidence map›Paper›PMID 33645419›Full record

ReviewPharmaceutical biology2021

A review of anti-inflammatory, antioxidant, and immunomodulatory effects of

Narges Marefati, Vahideh Ghorani, Farzaneh Shakeri, Marzie Boskabady, Farzaneh Kianian, Ramin Rezaee, Mohammad Hosein Boskabady

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
26.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 162 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Comprehensive Chemical Profiling and Assessment ofJournal of pharmacopuncture · 2026
    Article
  6. Article
  7. Article
  8. Open veterinary journal · 2026
    Article
  9. Pharmaceutics · 2026
    Article
  10. Review
  11. Onion (Food science & nutrition · 2026
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. The Potential Mechanisms ofDrug design, development and therapy · 2025
    Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Narges MarefatiApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Vahideh GhoraniApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Farzaneh ShakeriNatural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Marzie BoskabadyDental Materials Research Center and Department of Pediatric Dentistry, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Farzaneh KianianDepartment of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Ramin RezaeeClinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Hosein BoskabadyApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IRNorth Khorasan University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

context

objectiveAnti-inflammatory, antioxidant, and immunomodulatory effects of

methodsDatabases including, Web of Knowledge, Medline/PubMed, Scopus, and Google Scholar were checked for articles published between 1996 and the end of July 2020, using the key-words Allium cepa, quercetin, anti-inflammatory, antioxidant and immunomodulatory.

results

conclusionsThe effect of onion and its constituents on oxidative stress, inflammatory and immune system were shown indicating their therapeutic value in treatment of various diseases associated with oxidative stress, inflammation, and immune-dysregulation.

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsHumansImmune System DiseasesImmunologic FactorsInflammationOnionsOxidative StressPlant ExtractsAnti-Inflammatory AgentsAntioxidantsImmunologic FactorsPlant ExtractsflavonoidsinflammationOnionoxidative stressphenolicquercetin

Identifiers

PMID33645419
PMCPMC7919894
OpenAlexW3133863742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.