Evidence map›Paper›PMID 33645257›Full record

ArticleJournal of diabetes science and technology2022

A New Meal Absorption Model for Artificial Pancreas Systems.

Travis Diamond, Faye Cameron, B Wayne Bequette

Abstract read
In one paragraph

Article in Journal of diabetes science and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Travis DiamondDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.ORCID 0000-0001-5659-1872
Faye CameronDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.
B Wayne BequetteDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.ORCID 0000-0002-6472-1902

Funding

A probabilistic closed-loop artificial pancreas to handle unannounced meals R01DK102188 · NIDDK · RENSSELAER POLYTECHNIC INSTITUTE · PI BEQUETTE, B. WAYNE, BUCKINGHAM, BRUCE A · 2014 to 2016
$1.0M
NIDDK NIH HHS R01 DK102188
6 · The paper itself

Abstract

backgroundArtificial pancreas (AP) systems reduce the treatment burden of Type 1 Diabetes by automatically regulating blood glucose (BG) levels. While many disturbances stand in the way of fully closed-loop (automated) control, unannounced meals remain the greatest challenge. Furthermore, different types of meals can have significantly different glucose responses, further increasing the uncertainty surrounding the meal.

methodsEffective attenuation of a meal requires quick

resultsUsing gold-standard triple tracer meal data, the proposed VH model is compared to three simpler second-order response models. The proposed VH model increased model fit capacity by 22% and prediction accuracy by 12% relative to the next best models. A 47% increase in the accuracy of uncertainty predictions was also found. In a simple control scenario, the controller governed by the proposed VH model provided insulin just as fast or faster than the controller governed by the other models in four out of the six meals. While the controllers governed by the other models all delivered at least a 25% excess of insulin at their worst, the VH model controller only delivered 9% excess at its worst.

conclusionsThe VH Model performed best in accuracy metrics and succeeded over the other models in providing insulin quickly

Indexed as

Diabetes Mellitus, Type 1Pancreas, ArtificialAlgorithmsBlood GlucoseBlood Glucose Self-MonitoringHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsMealsBlood GlucoseHypoglycemic AgentsInsulinartificial pancreasautomated insulin deliveryblood glucose controlmeal predictionmodel predictive controltriple tracer

Identifiers

PMID33645257
PMCPMC8875069

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.