Evidence map›Paper›PMID 33645231›Full record

ArticleMolecular pharmaceutics2021

Development of a Prodrug of Camptothecin for Enhanced Treatment of Glioblastoma Multiforme.

Elisa Checa-Chavarria, Eva Rivero-Buceta, Miguel Angel Sanchez Martos, Gema Martinez Navarrete, Cristina Soto-Sánchez, Pablo Botella, Eduardo Fernández

Open access · hybridAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elisa Checa-ChavarriaInstitute of Bioengineering, Universidad Miguel Hernández, Elche, Spain and Centre for Network Biomedical Research (CIBER-BBN), Avenida de la Universidad s/n, 03202 Elche, Spain.
Eva Rivero-BucetaInstituto de Tecnología Química, Universitat Politècnica de València-Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022 Valencia, Spain.
Miguel Angel Sanchez MartosInstitute of Bioengineering, Universidad Miguel Hernández, Elche, Spain and Centre for Network Biomedical Research (CIBER-BBN), Avenida de la Universidad s/n, 03202 Elche, Spain.
Gema Martinez NavarreteInstitute of Bioengineering, Universidad Miguel Hernández, Elche, Spain and Centre for Network Biomedical Research (CIBER-BBN), Avenida de la Universidad s/n, 03202 Elche, Spain.
Cristina Soto-SánchezInstitute of Bioengineering, Universidad Miguel Hernández, Elche, Spain and Centre for Network Biomedical Research (CIBER-BBN), Avenida de la Universidad s/n, 03202 Elche, Spain.
Pablo BotellaInstituto de Tecnología Química, Universitat Politècnica de València-Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022 Valencia, Spain.ORCID 0000-0003-2141-3069
Eduardo FernándezInstitute of Bioengineering, Universidad Miguel Hernández, Elche, Spain and Centre for Network Biomedical Research (CIBER-BBN), Avenida de la Universidad s/n, 03202 Elche, Spain.
Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ESConsejo Superior de Investigaciones Científicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel therapeutic approach for glioblastoma multiforme (GBM) therapy has been carried out through

Indexed as

AnimalsAntineoplastic AgentsApoptosisAstrocytesBrain NeoplasmsCamptothecinCell Line, TumorCells, CulturedCell SurvivalCerebral CortexDisease Models, AnimalDrug Screening Assays, AntitumorFemaleGlioblastomaHumansMaleAntineoplastic AgentsCamptothecinProdrugs5-aminolevulinic acidblood−brain barriercamptothecinglioblastoma multiformetargeting

Identifiers

PMID33645231
PMCPMC8482753
OpenAlexW3133978623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.