ArticleLasers in medical science2021
Effects of diode low-level laser therapy on healing of tooth extraction sockets: a histopathological study in diabetic rats.
Article in Lasers in medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Laser-assisted pontic site soft tissue healing prior to fixed partial dentures: a randomized placebo-controlled clinical trial.BMC oral health · 2026Trial
- Effect of immediate photobiomodulation on pain and inflammation after oral biopsy: A randomized clinical study.Clinical oral investigations · 2026Trial
- Clinical and thermographic evaluation after lower third molar extractions and the application of different photobiomodulation protocols: double-blind randomised clinical trial.Clinical oral investigations · 2024Trial
- Autologous Platelet Concentrates and Photobiomodulation as Biologically Active Modifiers of Hard and Soft Tissue Healing: A Randomised Controlled Trial.Journal of functional biomaterials · 2026Article
- Photobiomodulation therapy reduces diabetic periodontal damage through modulation of macrophage metabolism and functions.Lasers in medical science · 2026Article
- Diabetes in spotlight: current knowledge and perspectives of photobiomodulation utilization.Frontiers in endocrinology · 2024Review
- The impact of immediate versus delayed mini-screw placement on alveolar bone preservation and bone density following tooth extraction: evidence from a canine model.BMC oral health · 2023Article
- Nd:YAG-photobiomodulation enhanced ADSCs multilineage differentiation and immunomodulation potentials.Lasers in medical science · 2023Article
- Efficacy of Low-Level Laser Therapy in Wound Healing and Pain Reduction After Gingivectomy: A Systematic Review and Meta-analysis.Journal of lasers in medical sciences · 2023Review
- Pathogenesis and treatment of wound healing in patients with diabetes after tooth extraction.Frontiers in endocrinology · 2022Review
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Diabetes mellitus is mostly interrelated to deficiency in wound healing. Low-level laser therapy has been shown to exert reliable effects on the acceleration of wound healing process. This study aimed to determine the potential influence of low-level laser therapy (LLLT) on the healing of extraction sockets in diabetic rats. A total of 24 healthy male Wistar rats were selected for this study. After diabetes induction, the maxillary first molars of all rats were extracted bilaterally. Then, the animals were subjected either to Ga-Al-As laser at 808 nm or to Al-Ga-In-P laser at 660 nm at the right extracted socket every day for the next 14 days. The left sockets served as controls. Rats were sacrificed on the 3rd, 5th, 7th, and 14th days after tooth extraction. The samples were examined by a pathologist. LLLT at 808 nm was able to significantly repress inflammation, improve osteoid formation, and promote vascularization in comparison to the non-treated sockets. LLLT at 660 nm significantly suppressed inflammation and developed vascularization in comparison to the non-treated sockets, but failed to improve osteoid formation in the treated sockets. This study suggests that LLLT could be considered as a reliable treatment for wound healing in diabetic experimental rats.
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