Evidence map›Paper›PMID 33644806›Full record

ArticleAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2021

Characteristics and Outcomes of Clinic Visits Immediately Preceding Sepsis Hospitalization.

H Catherine Miller, Vincent X Liu, Hallie C Prescott

Abstract read
In one paragraph

Article in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

H Catherine MillerH. Catherine Miller is a former internal medicine resident physician, University of Michigan, Ann Arbor. She is now an assistant professor of clinical medicine at Vanderbilt University Medical Center, Nashville, Tennessee.
Vincent X LiuVincent X. Liu is a research scientist, Kaiser Permanente Northern California Division of Research, Oakland, California and an intensivist, Kaiser Permanente Santa Clara Medical Center, Santa Clara, California.
Hallie C PrescottHallie C. Prescott is an associate professor, Department of Internal Medicine, University of Michigan and a core investigator, US Department of Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan.

Funding

Identifying pre-sepsis opportunities for early, targeted intervention - Equipment SupplementR35GM128672 · NIGMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI Vincent Liu · 2018 to 2026
$4.3M
General pathways and personalized risk of morbidity after sepsisK08GM115859 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PRESCOTT, HALLIE CHRISTINE · 2015 to 2018
$776k
NIGMS NIH HHS K08 GM115859NIGMS NIH HHS R35 GM128672
6 · The paper itself

Abstract

backgroundExisting sepsis quality improvement initiatives focus on recognition and treatment of sepsis upon hospital admission. Yet many patients are evaluated in the clinic within 1 day of sepsis hospitalization.

objectivesTo determine the circumstances of clinic visits that precede sepsis hospitalization, including illness severity, whether patients are referred to the hospital, and time lapse and change in illness severity between clinic and hospital evaluation.

methodsIn a retrospective cohort study at a tertiary academic medical center, data from electronic medical records were collected for all adult patients evaluated in an outpatient clinic within 1 day of sepsis hospitalization in 2017.

resultsOf 1450 patients hospitalized with sepsis, 118 had an established outpatient provider and a clinic visit within 1 day of admission and thus were included. During the clinic visit, 47 patients (39.8%) had a quick Sequential Organ Failure Assessment (qSOFA) score ≥1, and 59 (50.0%) had vital sign abnormalities. Most (74, 62.7%) were sent directly to the emergency department or hospital. Upon emergency department/hospital presentation, 62 patients (52.5%) had a worsening qSOFA score and/ or vital signs and 27 (22.9%) had worsening of multiple parameters. Median time lapse from clinic to emergency department/hospital evaluation was 3.2 hours.

conclusionsOne in 10 patients hospitalized for sepsis had been evaluated in a clinic within 1 day of admission. At that clinic visit, most patients had an elevated qSOFA score or abnormal vital signs and a majority were sent directly to the emergency department/hospital. Half experienced clinical deterioration between the clinic visit and arrival in the emergency department/hospital.

Indexed as

Ambulatory CareHospitalizationSepsisAdultAmbulatory Care FacilitiesEmergency Service, HospitalHospital MortalityHumansPrognosisRetrospective StudiesROC CurveSeverity of Illness Index

Identifiers

PMID33644806
PMCPMC8789345

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.