Evidence map›Paper›PMID 33644777›Full record

ArticleJournal of the American College of Emergency Physicians open2021

Understanding timely STEMI treatment performance: A 3-year retrospective cohort study using diagnosis-to-balloon-time and care subintervals.

Maame Yaa A B Yiadom, Olayemi O Olubowale, Cathy A Jenkins, Karen F Miller, Jennifer L West, Timothy J Vogus, Christoph U Lehmann, Victoria D Antonello, Gordon R Bernard, Alan B Storrow and 2 more

Abstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maame Yaa A B YiadomDepartment of Emergency Medicine Vanderbilt University Medical Center Nashville Tennessee USA.ORCID https://orcid.org/0000-0002-6479-0764
Olayemi O OlubowaleDepartment of Emergency Medicine Vanderbilt University Medical Center Nashville Tennessee USA.
Cathy A JenkinsDepartment of Biostatistics Vanderbilt University Medical Center Nashville Tennessee USA.
Karen F MillerDepartment of Emergency Medicine Vanderbilt University Medical Center Nashville Tennessee USA.
Jennifer L WestDepartment of Emergency Medicine Vanderbilt University Medical Center Nashville Tennessee USA.
Timothy J VogusOwen Graduate School of Management Vanderbilt University Nashville Tennessee USA.
Christoph U LehmannDepartment of Biomedical Informatics & Pediatrics Vanderbilt University Medical Center Nashville Tennessee USA.
Victoria D AntonelloDepartment of Emergency Medicine Vanderbilt University Medical Center Nashville Tennessee USA.
Gordon R BernardDepartment of Medicine, Division of Critical Care Vanderbilt University Medical Center Nashville Tennessee USA.
Alan B StorrowDepartment of Emergency Medicine Vanderbilt University Medical Center Nashville Tennessee USA.
Christopher J LindsellDepartment of Biostatistics Vanderbilt University Medical Center Nashville Tennessee USA.
Dandan LiuDepartment of Biostatistics Vanderbilt University Medical Center Nashville Tennessee USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFrom the perspective of percutaneous coronary intervention (PCI) centers, locations of ST-segment elevation myocardial infarction (STEMI) diagnosis can include a referring facility, emergency medical services (EMS) transporting to a PCI center, or the PCI center's emergency department (ED). This challenges the use of door-to-balloon-time as the primary evaluative measure of STEMI treatment pathways. Our objective was to identify opportunities to improve care by quantifying differences in the timeliness of STEMI treatment mobilization based on the location of the diagnostic ECG.

methodsThis 3-year, single-center, retrospective cohort study classified patients by diagnostic ECG location: referring facility, EMS, or PCI center ED. We quantified door-to-balloon-time and diagnosis-to-balloon-time with its care subintervals.

resultsOf 207 ED STEMI patients, 180 (87%) received PCI. Median diagnosis-to-balloon-times were shortest among the ED-diagnosed (78 minutes [interquartile range (IQR), 61-92]), followed by EMS-identified patients (89 minutes [IQR, 78-122]), and longest among those referred (140 minutes [IQR, 119-160]), reflecting time for transport to the PCI center. Conversely, referred patients had the shortest median door-to-balloon-times (38 minutes [IQR, 34-43]), followed by the EMS-identified (64 minutes [IQR, 47-77]), whereas ED-diagnosed patients had the longest (89 minutes [IQR, 70-114]), reflecting diagnosis and catheterization lab activation frequently occurring before PCI center ED arrival for referred and EMS-identified patients.

conclusionsDiagnosis-to-balloon-time and its care subintervals are complementary to the traditional door-to-balloon-times as measures of the STEMI treatment process. Together, they highlight opportunities to improve timely identification among ED-diagnosed patients, use of out-of-hospital cath lab activation for EMS-identified patients, and encourage pathways for referred patients to bypass PCI center EDs.

Indexed as

cardiovascular emergencydiagnosis‐to‐balloondoor‐to‐balloonemergency caremyocardial infarctionSTEMISTEMI care systemtimely caretime‐to‐treatment

Identifiers

PMID33644777
PMCPMC7890036

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.