Evidence map›Paper›PMID 33644623›Full record

ArticleJournal of the Endocrine Society2021

Flash CGM Is Associated With Reduced Diabetes Events and Hospitalizations in Insulin-Treated Type 2 Diabetes.

Richard M Bergenstal, Matthew S D Kerr, Gregory J Roberts, Diana Souto, Yelena Nabutovsky, Irl B Hirsch

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05840250 naterminatednot on this mapstarted 2023, after this paper: background citation

Improving Glucose Control and Self-Management in Adults With Type 2 Diabetes From Health Disparate Groups Using Continuous Glucose Monitoring and Education Support

TypeinterventionalSponsorHackensack Meridian HealthRan2023 to 2024Enrolled10ConditionsDiabetesArmsContinuous Glucose Monitoring and Education Support
NCT06624553 phase2completednot on this mapstarted 2022, after this paper: background citation

Effect of Monitoring With Freestyle Libre 2 Glucose Sensor on Treatment Satisfaction in Patients With Type 2 Diabetes Mellitus: Exploratory Study in Patients Starting Monitoring

TypeinterventionalSponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2022 to 2023Enrolled50ConditionsDiabetes Mellitus, Type 2ArmsFreeStyle Libre 2, flash glucose monitoring
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 81 citations in OpenAlex.

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  11. Clin-STAR Corner: Practice Changing Advances in Diabetes Care.Journal of the American Geriatrics Society · 2025
    Review
  12. Article
  13. Narrative Review: Continuous Glucose Monitoring (CGM) in Older Adults with Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Review
  14. Article
  15. The role of advanced technologies in improving diabetes outcomes.The American journal of managed care · 2025
    Review
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  19. Cost-Effectiveness of FreeStyle Libre for Glucose Self-Management Among People with Diabetes Mellitus: A Canadian Private Payer Perspective.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Richard M BergenstalInternational Diabetes Center, Park Nicollet and HealthPartners, Minneapolis, MN, USA.ORCID https://orcid.org/0000-0002-9050-5584
Matthew S D KerrAbbott, Sylmar, CA, USA.
Gregory J RobertsAbbott, Sylmar, CA, USA.
Diana SoutoAbbott Diabetes Care, Alameda, CA, USA.
Yelena NabutovskyAbbott, Sylmar, CA, USA.
Irl B HirschUniversity of Washington School of Medicine, Seattle, WA, USA.
Danaher (United States) · USDiabetes Care Center · USPark Nicollet Clinic · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSuboptimal glycemic control among individuals with diabetes is a leading cause of hospitalizations and emergency department utilization. Use of flash continuous glucose monitoring (flash CGM) improves glycemic control in type 1 and type 2 diabetes, which may result in lower risk for acute and chronic complications that require emergency services and/or hospitalizations.

methodsIn this retrospective, real-world study, we analyzed IBM MarketScan Commercial Claims and Medicare Supplemental databases to assess the impact of flash CGM on diabetes-related events and hospitalizations in a cohort of 2463 individuals with type 2 diabetes who were on short- or rapid-acting insulin therapy. Outcomes were changes in acute diabetes-related events (ADE) and all-cause inpatient hospitalizations (ACH), occurring during the first 6 months after acquiring the flash CGM system compared with event rates during the 6 months prior to system acquisition. ICD-10 codes were used to identify ADE for hypoglycemia, hypoglycemic coma, hyperglycemia, diabetic ketoacidosis, and hyperosmolarity.

resultsADE rates decreased from 0.180 to 0.072 events/patient-year (hazard ratio [HR]: 0.39 [0.30, 0.51];

conclusionsAcquisition of the flash CGM system was associated with reductions in ADE and ACH. These findings provide support for the use of flash CGM in type 2 diabetes patients treated with short- or rapid-acting insulin therapy to improve clinical outcomes and potentially reduce costs.

Indexed as

continuous glucose monitoringhospitalizationshyperglycemiahypoglycemiatype 2 diabetes

Identifiers

PMID33644623
PMCPMC7901259
OpenAlexW3126724397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.