ArticleAmerican journal of ophthalmology case reports2021
Macular thickness analysis and resolution of subretinal drusenoid deposits with optical coherence tomography in vitamin A deficiency-related retinopathy.
Article in American journal of ophthalmology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Micronutrient deficiencies in hepatic cirrhosis: Navigating challenges to assessment and implications for clinical management: A narrative review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Review
- Vitamin A Deficiency Screening in Patients With Chronic Alcohol-Associated Liver Disease: Implications for Liver Transplant Candidates.ACG case reports journal · 2023Article
- Bilateral compressive optic neuropathy and outer retinopathy due to optic canal hyperostosis in a child with isolated vitamin a deficiency.Documenta ophthalmologica. Advances in ophthalmology · 2023Article
- Posterior placoid-like maculopathy and macular hole associated with vitamin A deficiency.American journal of ophthalmology case reports · 2023Article
- Choroidal Thickening and Outer Retinal Alterations in Vitamin A Deficiency: A Case Report.Case reports in ophthalmologyArticle
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
purposeTo report the resolution of subretinal drusenoid deposits (SDDs) and the changes in macular thickness at various segmentation levels in a patient who was treated for vitamin A deficiency-related retinopathy. OBSERVATIONS: A 67-year-old man with cirrhosis secondary to hepatitis C was referred for unexplained vision decline and nyctalopia. He was diagnosed with vitamin A deficiency after he was found to have yellow-white drusen-like deposits in the posterior pole and midperiphery, which corresponded to SDDs on optical coherence tomography (OCT). Treatment with vitamin A supplementation was initiated, and, over the course of eight months, the symptoms improved, the SDDs resolved, and retinal thickness generally increased, although the rate and pattern of change differed depending on the macular quadrant and the segmentation layer being analyzed. CONCLUSIONS AND IMPORTANCE: Vitamin A deficiency should be considered in patients with liver disease who present with drusen-like deposits in the macula and midperiphery. Prompt recognition and treatment may improve symptoms and reverse some retinal pathology, including the presence of SDDs. Vitamin A supplementation in these patients seems to affect the inner retina and outer retina differently.
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