Evidence map›Paper›PMID 33644483›Full record

ArticleProgress in rehabilitation medicine2021

Effects of Lee Silverman Voice Treatment (LSVT LOUD) on Swallowing in Patients with Progressive Supranuclear Palsy: A Pilot Study.

Sonoko Nozaki, Masako Fujiu-Kurachi, Takako Tanimura, Kimiyo Ishizuka, Eri Miyata, Shuhei Sugishita, Takahisa Imai, Maiko Nishiguchi, Mitsuru Furuta, Shiro Yorifuji

Open access · diamondAbstract read
In one paragraph

Article in Progress in rehabilitation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Voice and Speech in Atypical Parkinsonian Disorders.Movement disorders clinical practice · 2026
    Review
  3. Article
  4. Voice Meets Swallowing: A Scoping Review of Therapeutic Connections.American journal of speech-language pathology · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sonoko NozakiWakakusa Tatsuma Rehabilitation Hospital, Daito, Japan.
Masako Fujiu-KurachiInternational University of Health and Welfare, Narita, Japan.
Takako TanimuraKansai Rosai Hospital, Amagasaki, Japan.
Kimiyo IshizukaKansai Rosai Hospital, Amagasaki, Japan.
Eri MiyataKansai Medical University Hospital, Hirakata, Japan.
Shuhei SugishitaTakasago Municipal Hospital, Takasago, Japan.
Takahisa ImaiAshiya Municipal Hospital, Ashiya, Japan.
Maiko NishiguchiKansai Rosai Hospital, Amagasaki, Japan.
Mitsuru FurutaKansai Rosai Hospital, Amagasaki, Japan.
Shiro YorifujiKansai Rosai Hospital, Amagasaki, Japan.
Kansai Rosai Hospital · JPAshiya University · JPInternational University of Health and Welfare · JPKansai Medical University · JPTakasago (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesProgressive supranuclear palsy (PSP) is an uncommon progressive neurodegenerative disease with no effective cure at present. The initial symptoms resemble those of Parkinson's disease; however, the prevalence of PSP is about one-tenth that of Parkinson's disease. In many cases, dysphagia is severe, and the development of dysphagia is an early predictor of life expectancy. The aim of the current study was to define the effects of Lee Silverman Voice Treatment (LSVT LOUD) on swallowing and voice/speech in seven patients with PSP.

methods: Each patient underwent swallowing and voice/speech evaluations before and after 4 weeks of LSVT. Swallowing motility disorders were defined, temporal measures of swallowing were determined by videofluoroscopic evaluation, and voice measures of maximum phonation and speech intelligibility in reading and monologue were examined.

resultsAfter LSVT, the median duration of opening of the upper esophageal sphincter (from the beginning of the posterior movement of the bolus to upper esophageal sphincter opening) on videofluoroscopy was significantly shortened from 0.42 to 0.38 s (Wilcoxon signed-rank test P=0.016). The oral transit duration was decreased in five patients, but the decrease was not significant. Voice changes after LSVT included increases in voice intensity and in sustained duration were not significant.

conclusionIn this small study, it was found that LSVT may improve swallowing functions in patients with PSP.

Indexed as

dysphagiaLSVTprogressive supranuclear palsyvoice treatment

Identifiers

PMID33644483
PMCPMC7897538
OpenAlexW3132234683

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.