Evidence map›Paper›PMID 33644296›Full record

ArticleInternational journal of cardiology. Heart & vasculature2021

Treatment of acute cardiac tamponade: A retrospective analysis of classical intermittent versus continuous pericardial drainage.

Christopher Stremmel, Clemens Scherer, Enzo Lüsebrink, Danny Kupka, Teresa Schmid, Thomas Stocker, Antonia Kellnar, Jan Kleeberger, Moritz F Sinner, Tobias Petzold and 6 more

Abstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Atypical cardiac tamponade associated with pericardial-epicardial adhesions following bicycle trauma.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. New challenges in cardiac intensive care units.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Christopher StremmelMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Clemens SchererMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Enzo LüsebrinkMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Danny KupkaMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Teresa SchmidMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Thomas StockerMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Antonia KellnarMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Jan KleebergerMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Moritz F SinnerMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Tobias PetzoldMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Julinda MehilliDZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Klinikum der Universität München, Munich, Germany.
Daniel BraunMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Mathias OrbanMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Jörg HausleiterMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Steffen MassbergMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Martin OrbanMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute cardiac tamponade is a life-threatening pathology in modern cardiology as catheter-based interventions become increasingly relevant. Pericardiocentesis is usually the primary treatment of choice. However, protocols for handling of draining pigtail catheters are very variable due to limit data and require further investigation.

methodsWe retrospectively analyzed 52 patients with acute cardiac tamponade requiring immediate pericardiocentesis from January 2017 to August 2020. Patients were treated with a classical approach of intermittent manual aspiration or continuous pericardial drainage using a redon drainage system.

resultsMean age of patients was 74 years in both groups. Most common causes for cardiac tamponade were percutaneous coronary interventions in about 50% and transaortic valve implantations in 25% of all cases. 28 patients were treated with classic intermittent drainage from 2017 to 2020. 24 patients were treated with continuous drainage from December 2018-2020. Compared to classical intermittent drainage treatment, continuous drainage was associated with a lower rate of a surgical intervention or cardiac re-tamponade and a lower mortality at 5 days (HR 0.2, 95% CI 0.1-0.9, log-rank p = 0.03). Despite a longer total drainage time under continuous suction, drainage volumes were comparable in both groups.

conclusionAcute cardiac tamponade can be efficiently treated by pericardiocentesis with subsequent continuous negative pressure drainage via a pigtail catheter. Our retrospective analysis shows a significantly lower mortality, a decreased rate of interventions and lower rates of cardiac re-tamponade without any relevant side effects when compared to classical intermittent manual drainage. These findings require further investigations in larger, randomized trials.

Indexed as

cont., continiuousDrainageInterventionint., intermittentPericardial effusionPericardiocentesisTamponade

Identifiers

PMID33644296
PMCPMC7887384

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.