ReviewFrontiers in pediatrics2020
Management of Patent Ductus Arteriosus in Premature Infants in 2020.
Review in Frontiers in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Dual medication therapy (acetaminophen and ibuprofen) for the management of patent ductus arteriosus in preterm infants: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2022Pooled it
- The efficiency and safety of low-dose intravenous indomethacin for closure of patent ductus arteriosus in preterm neonate: a randomized controlled trial.Scientific reports · 2025Trial
- Does use of acetaminophen and/or NSAIDs increase the risk of developing bronchopulmonary dysplasia?Pediatric research · 2026Article
- Preterm Children in Iceland: Neonatal Morbidities and Motor Development in the First Two Years, and Later Disability Diagnosis.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Identifying Factors Associated with Prolonged Postoperative Mechanical Ventilation in Preterm Infants Undergoing Patent Ductus Arteriosus Ligation Using Machine Learning and SHAP Analysis: A Large-Sample Single-Center Retrospective Analysis.Journal of clinical medicine · 2026Article
- Echocardiographic Predictors and Incidence of Left Ventricular Dysfunction Following Transcatheter Patent Ductus Arteriosus Closure in Extremely Premature Infants.Pediatric cardiology · 2026Article
- The Aortic Flow Reversal Ratio: A Quantitative Adjunct to the Bicêtre Score in Vein of Galen Malformation.Journal of clinical medicine · 2026Article
- Suspected Infective Endocarditis in a Premature Neonate After Patent Ductus Arteriosus Occluder Placement: A Case Report.Case reports in pediatrics · 2026Article
- SCAI Position Statement on Transcatheter Occlusion of Patent Ductus Arteriosus in Premature Infants.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Omic-signature of bronchopulmonary dysplasia associated pulmonary hypertension in <1500g-birth-weight-infants with hemodynamically significant intracardiac shunt.Pediatric research · 2025Article
- A Discourse on Percutaneous Closure of the Patent Ductus Arteriosus in Premature Neonates: Controversy, Remedy, or Paradox of Choice?CJC pediatric and congenital heart disease · 2025Review
- Early prediction of mortality and morbidities in VLBW preterm neonates using machine learning.Pediatric research · 2025Article
- Advancements in research on fluid overload in preterm infants-a narrative review.Frontiers in pediatrics · 2025Review
- Machine learning-based prediction of hemodynamically significant patent ductus arteriosus in preterm neonates: a pioneering insight.Frontiers in pediatrics · 2025Article
- Characteristics of Extremely Preterm Infants Undergoing Procedural Closure of Patent Ductus Arteriosus: A Retrospective Cohort Study.International journal of pediatrics · 2025Article
- Comparative Effectiveness of Surgical Ligation and Catheter Closure of Patent Ductus Arteriosus in Preterm Infants.Pediatric cardiology · 2024Article
- Factors Predicting Spontaneous Closure of Patent Ductus Arteriosus in Very Low Birth Weight Neonates.Cureus · 2024Article
- Review
- Hereditary TTP/Upshaw-Schulman syndrome: the ductus arteriosus controls newborn survival.International journal of hematology · 2024Review
- Current management of surgical neonates: is it optimal or do we need to improve? A national survey of the Italian Society of Neonatology.Pediatric surgery international · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The patent ductus arteriosus (PDA) is the most commonly found cardiac condition in neonates. While there have been several studies and thousands of publications on the topic, the decision to treat the PDA is still strongly debated among cardiologists, surgeons, and neonatologists. This is in part due to the shortage of long-term benefits with the interventions studied. Practice variations still exist within sub-specialties and centers. This article briefly summarizes the history, embryology and histology of the PDA. It also succinctly discusses the hemodynamic significance of a PDA which builds the framework to review all the available literature on PDA closure in premature infants, though not a paradigm shift just yet; it introduces transcatheter PDA closure (TCPC) as a possible armament to the clinician for this age-old problem.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.