Evidence map›Paper›PMID 33643872›Full record

ArticleIndian journal of endocrinology and metabolism

Radiofrequency Ablation of Parathyroid Adenomas: Safety and Efficacy in a Study of 10 Patients.

Anubhav Harish Khandelwal, Smarth Batra, Surabhi Jajodia, Saurabh Gupta, Rohit Khandelwal, Abhay Kumar Kapoor, Sunil Kumar Mishra, S S Baijal

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anubhav Harish KhandelwalDepartment of Interventional Radiology, Medanta-The Medicity, Gurugram, Haryana, India.
Smarth BatraDepartment of Interventional Radiology, Medanta-The Medicity, Gurugram, Haryana, India.
Surabhi JajodiaDepartment of Interventional Radiology, Medanta-The Medicity, Gurugram, Haryana, India.
Saurabh GuptaDepartment of Interventional Radiology, Medanta-The Medicity, Gurugram, Haryana, India.
Rohit KhandelwalDepartment of Interventional Radiology, Medanta-The Medicity, Gurugram, Haryana, India.
Abhay Kumar KapoorDepartment of Interventional Radiology, Medanta-The Medicity, Gurugram, Haryana, India.
Sunil Kumar MishraDepartment of Endocrinology and Metabolism, Medanta-The Medicity, Gurugram, Haryana, India.
S S BaijalDepartment of Interventional Radiology, Medanta-The Medicity, Gurugram, Haryana, India.
Medanta The Medicity · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate safety and effectiveness of ultrasound-guided percutaneous radiofrequency ablation of parathyroid adenoma in surgically unfit patients with hypercalcemia because of hyperparathyroidism. MATERIALS AND

methodsA retrospective review of hospital records from Jan 2012 to Dec 2018 revealed 10 patients, who had undergone ablation for solitary parathyroid adenoma. All 10 patients suffered from hyperparathyroidism because of parathyroid adenoma, resulting in hypercalcemia. These patients were surgically unfit because of comorbidities. Pre-ablation serum calcium and serum parathormone levels were measured and compared with the levels after the ablation.

resultsMean serum calcium level decreased significantly from 2.81 ± 0.17 mmol/L pre-ablation to 2.42 ± 0.17 mmol/L 72 h after ablation and parathyroid hormone levels became normal in all patients within 7 days. Seven patients remained normo-calcaemic at 6 months follow-up with no signs and symptoms of hyperparathyroidism. One patient with pancreatitis died after 15 days because of pre-existing multi-organ failure. Two patients were lost to follow-up before 6 months.

conclusionRadiofrequency ablation of parathyroid adenoma is a safe and effective alternate treatment method for symptomatic hypercalcemia in surgically unfit patients suffering from primary hyperparathyroidism because of parathyroid adenoma.

Indexed as

hyperparathyroidismHypesrcalcemiaparathyroid adenomaradiofrequency ablation

Identifiers

PMID33643872
PMCPMC7906106
OpenAlexW3120461112

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.